Liver Cirrhosis. Other and unspecified cirrhosis of liver
Conditions
Interventions
Intervention 1: Intervention group: The intervention will involve the consumption of the NBS dietary supplement for a duration of three months. The herbal NBS supplement will be administered to the in
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Age between 18 and 65 years Documented diagnosis of liver cirrhosis in the patient’s medical records Ability to provide written informed consent to participate in the study
Exclusion criteria
Exclusion criteria: Use of any other dietary supplements by the patient Presence of uncontrolled clinical or biochemical complications related to severe liver failure (hepatic encephalopathy, hepatorenal syndrome, gastrointestinal bleeding, serum bilirubin level greater than 5 mg/dL) History of hepatocellular carcinoma History of active alcoholism History of drug allergy or gluten sensitivity Women who are pregnant or breastfeeding during the study period Individuals with immunosuppressive diseases or taking immunosuppressive medications Individuals with autoimmune diseases History of infection within the past 3 months
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Liver function. Timepoint: Before the start of the intervention and three months after the start of the intervention. Method of measurement: Clinical symptoms, laboratory tests, imaging methods, and biopsy and histopathology. | — |
Secondary
| Measure | Time frame |
|---|---|
| Body Mass Index (BMI). Timepoint: Before the start of the intervention and three months after the start of the intervention. Method of measurement: Weight measured using a scale and height measured using a stadiometer.;Skeletal Muscle Index (SMI). Timepoint: Before the start of the intervention and three months after the start of the intervention. Method of measurement: Body analyzer device and formula.;Sarcopenia. Timepoint: Before the start of the intervention and three months after the start of the intervention. Method of measurement: hand grip strength meter.;Oxidative stress. Timepoint: Before the start of the intervention and three months after the start of the intervention. Method of measurement: ELISA kit. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaryam Jafari
Tehran University of Medical Sciences
Outcome results
None listed