rheumatoid arthritis. Rheumatoid arthritis with rheumatoid factor
Conditions
Interventions
Intervention 1: Intervention group 1: Hypoxic conditions and aerobic activity (arterial oxygen saturation percentage equal to breathing oxygen rate of 13%). Intervention 2: Intervention group 2: Normo
Sponsors
Razi University of Kermanshah
Eligibility
Sex/Gender
Male
Age
30 Years to 64 Years
Inclusion criteria
Inclusion criteria: Men with rheumatoid arthritis aged 30-64 Rheumatoid arthritis diagnosed and confirmed by a specialist (based on the criteria of the American College of Rheumatology and radiographic analysis) Having a history of rheumatoid arthritis for more than two years Low to moderate disease activity score in 28 joints (based on the DAS 28 index) Obtaining a certificate of non-restriction from a specialist to participate in an exercise program
Exclusion criteria
Exclusion criteria: Joint deformity in rheumatoid arthritis patients severe anemia tobacco and alcohol use
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Evaluation of serum interleukin-6 (IL-6) levels. Timepoint: Before and after aerobic activity in both hypoxic and normoxia conditions. Method of measurement: Blood sampling, Serum measurement by ELISA method.;C Reactive Protein (CRP). Timepoint: Before and after aerobic activity in both hypoxic and normoxia conditions. Method of measurement: Blood sampling, Serum measurement by ELISA method.;Erythrocyte Sedimentation Rate (ESR). Timepoint: Before and after aerobic activity in both hypoxic and normoxia conditions. Method of measurement: Blood sampling, special measurement kit.;Desease Activity Score (DAS-28). Timepoint: Before and after aerobic activity in both hypoxic and normoxia conditions. Method of measurement: Valid DAS-28 questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| Rating of Perceived Exertion. Timepoint: Every three minutes while performing aerobic activity. Method of measurement: Borg 6-20 scale.;Pain index. Timepoint: Every three minutes while performing aerobic activity. Method of measurement: Visual analog scale 0 - 10.;Sleep quality. Timepoint: The night after performing aerobic activity. Method of measurement: Groningen sleep Questionnaire.;Review of well-being questionnaire scores. Timepoint: The night after performing aerobic activity. Method of measurement: Well-Being Questionnaire.;Review of health assessment questionnaire scores. Timepoint: Initially, every session and a week thereafter. Method of measurement: Health Assessment Questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactVahid Tadibi
Razi University of Kermanshah
Outcome results
None listed