Postoperative Pain Management in Patients Undergoing Elective Laparoscopic Cholecystectomy. Other acute postprocedural pain
Conditions
Interventions
Intervention 1: Intervention group: Participants in this group will receive an intravenous bolus of lidocaine during surgery. Lidocaine hydrochloride 2% solution (manufactured by Shahid Ghazi, Iran) w
Sponsors
Babol University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Adult patients aged 18 years or older. Patients scheduled for elective laparoscopic cholecystectomy. Classified as ASA physical status I or II. Ability to provide informed consent. No known contraindications or hypersensitivity to lidocaine.
Exclusion criteria
Exclusion criteria: Known allergy or hypersensitivity to lidocaine or other amide-type local anesthetics Significant hepatic or renal dysfunction. History of severe cardiac arrhythmias or conduction abnormalities. Pregnant or breastfeeding women. Patients undergoing emergency surgery Presence of chronic pain conditions requiring regular opioid treatment. Any contraindication to general anesthesia. Inability to provide valid informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative pain intensity (VAS score) in patients undergoing laparoscopic cholecystectomy under general anesthesia. Timepoint: 1 hour after recovery from general anesthesia. Method of measurement: Visual Analogue Scale (VAS), 10 cm line from 0 (no pain) to 10 (worst imaginable pain). | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of postoperative vomiting within the first 24 hours after surgery. Timepoint: Continuously during the first 24 hours after surgery. Method of measurement: Assessed by direct patient questioning and clinical observation by trained anesthesia staff.;Need for postoperative antiemetic (ondansetron) within the first 24 hours after surgery. Timepoint: Continuously during the first 24 hours after surgery. Method of measurement: Recorded when ondansetron is administered following any episode of postoperative nausea or vomiting.;Total dose of ondansetron administered (mg) during the first 24 hours after surgery. Timepoint: Within the first 24 hours after surgery. Method of measurement: Cumulative dose recorded by anesthesia staff.;Incidence of lidocaine-related adverse effects during and after surgery. Timepoint: From start of lidocaine administration until 48 hours after surgery. Method of measurement: Clinical monitoring and documentation of symptoms such as cardiovascular, neurologic, dermatologic, or gastrointestinal adverse events.;Need for postoperative analgesia (pethidine). Timepoint: During the first 24 hours after surgery. Method of measurement: Based on VAS score = 4; pethidine administered and recorded. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMarjan Khoshnevis
Babol University of Medical Sciences
Outcome results
None listed