Comparison of the effects of propolis and chlorhexidine mouthwash on oral health and impacted mandibular wisdom teeth

Studying the effect of herbal mouthwash (propolis) on the reduction of gingival index, plaque index, and prevalence of dry socket in impacted mandibular wisdom teeth compared to chlorhexidine

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20241211064021N4

Enrollment

Registered

2025-03-21

Start date

2025-04-12

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Studying the effect of herbal mouthwash (propolis) on the reduction of gingival index, plaque index, and prevalence of dry socket in impacted mandibular wisdom teeth compared to chlorhexidine. Chronic gingivitis

Interventions

Intervention 1: Intervention group: The effect of herbal mouthwash (propolis) is to rinse your mouth with 10 ml of mouthwash for 30 seconds, one hour after brushing your teeth, twice a day (morning an

Eligibility

Sex/Gender

All

Age

15 Years to 30 Years

Inclusion criteria

Inclusion criteria: Having impacted wisdom teeth in the lower jaw Not using other mouthwashes Plaque index and gum index

Exclusion criteria

Exclusion criteria: Pregnant people People with cardiovascular problems People who use antibiotic medications for any reason

Design outcomes

Primary

Measure	Time frame
The amount of gum index reduction. Timepoint: Before intervention: Assessment of the initial condition before starting to use the mouthwash. After intervention: Assessment at specific times after the start of treatment, measured on days 7 and 14. Method of measurement: They are measured using standard clinical methods, which include examination of the teeth and gums by a trained dentist and researcher. Instruments such as a probe are used to measure the depth of the gingival pocket or visual observation is used to determine the presence of plaque.;Prevalence of dry cavity. Timepoint: Before intervention: Assessment of the initial condition before starting to use the mouthwash. After intervention: Assessment at specific times after the start of treatment, measured on days 7 and 14. Method of measurement: It is usually assessed through clinical records and reports of complications from patients after wisdom tooth extraction.	—

Measure

Time frame

The amount of gum index reduction. Timepoint: Before intervention: Assessment of the initial condition before starting to use the mouthwash. After intervention: Assessment at specific times after the start of treatment, measured on days 7 and 14. Method of measurement: They are measured using standard clinical methods, which include examination of the teeth and gums by a trained dentist and researcher. Instruments such as a probe are used to measure the depth of the gingival pocket or visual observation is used to determine the presence of plaque.;Prevalence of dry cavity. Timepoint: Before intervention: Assessment of the initial condition before starting to use the mouthwash. After intervention: Assessment at specific times after the start of treatment, measured on days 7 and 14. Method of measurement: It is usually assessed through clinical records and reports of complications from patients after wisdom tooth extraction.

—

Secondary

Measure	Time frame
Patients' perception of pain or discomfort. Timepoint: Before the intervention: To assess the initial condition of the patients. During the intervention: Periodic assessment (every week and every month) to observe changes. Method of measurement: It is measured through rating scales (such as a 0 to 10 rating scale) in which patients report their level of pain.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactPouria Karimi

Hamedan University of Medical Sciences

atmonero@gmail.com+98 81 3131 0000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026