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Evaluation of the effect of adding dexmedetomidine to 0.5% hyperbaric bupivacaine on the quality of spinal anesthesia in lower limb surgeries

Evaluation of the effect of adding dexmedetomidine to 0.5% hyperbaric bupivacaine on the quality of spinal anesthesia in lower limb surgeries

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20241211064021N14
Enrollment
60
Registered
2026-01-04
Start date
2026-01-05
Completion date
Unknown
Last updated
2026-02-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Studying the effect of dexmedetomidine on improving the quality of spinal anesthesia with bupivacaine in lower limb surgeries. Osteoarthritis of knee

Interventions

Intervention 1: In the intervention group, patients will receive dexmedetomidine. The drug is administered at a dose of 0.5 micrograms per kilogram of body weight as a slow intravenous infusion over 1

Sponsors

Hamedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
25 Years to 65 Years

Inclusion criteria

Inclusion criteria: Age between 18 and 65 years No use of drugs affecting the central nervous system and anesthesia within the past 24 hours. Informed consent to participate in the study

Exclusion criteria

Exclusion criteria: history of hypertension allergies to the drugs being studied

Design outcomes

Primary

MeasureTime frame
Severity of pain after surgery in the early hours. Timepoint: At intervals of 6, 12 and 24 hours after the completion of surgery. Method of measurement: Visual Pain Scale and Numerical Pain Scale.

Secondary

MeasureTime frame
Duration of need for oral painkillers. Timepoint: Until discharge. Method of measurement: Record the number of days the patient required oral painkillers (other than usual home remedies) to control pain.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactEbadollah Fadaei Athar

Hamedan University of Medical Sciences

fadaeiebad@gmail.com+98 81 3131 0000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 7, 2026