The effect of dermal matrix on the thickness and aesthetics of soft tissue around implants

Investigating the effect of acellular dermal matrix on the vertical thickness of peri-implant soft tissue: a clinical and histological study

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20241211064021N10

Enrollment

243

Registered

2025-10-13

Start date

2025-10-25

Completion date

Unknown

Last updated

2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Vertical thickness of soft tissue around dental implants in patients with mandibular partial edentulism. Complete loss of teeth due to periodontal diseases

Interventions

Intervention 1: Intervention group: Implant recipient + acellular dermal matrix (ADM): Primary treatment: DIO (Korea) implants were implanted, followed immediately by an acellular dermal matrix (ADM)

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients must have a thin biotype (vertical soft tissue thickness less than 2 mm) Patients should be 6 months post-tooth extraction and initial soft and hard tissue repair.

Exclusion criteria

Exclusion criteria: Medical conditions that contraindicate implants A history of periodontitis

Design outcomes

Primary

Measure	Time frame
Increased vertical thickness of soft tissue. Timepoint: 3 months after implant surgery (exposing at the time of surgery). Method of measurement: Measurement with a standard periodontal probe.	—

Secondary

Measure	Time frame
Surgical success rate. Timepoint: 3 months after surgery. Method of measurement: Re-measurement of vertical soft tissue thickness.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAtusa Haqdoost

Hamedan University of Medical Sciences

haghdoost.research@gmail.com+98 81 3131 0000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026