The effect of topical insulin on oral lichen planus

Investigating the effect of topical insulin in comparison of placebo in the treatment of patients with oral lichen planus

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20241208063991N1

Enrollment

Registered

2025-05-16

Start date

2025-04-19

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Oral Lichen planus. Lichen planus, unspecified

Interventions

Intervention 1: Intervention group: 19 patients receive topical insulin, 1 cc of regular topical insulin, 2 units per cc, twice daily for 3 months. Patients will be visited monthly and lesion size wil

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with a confirmed diagnosis of Oral Lichen Planus From any age group

Exclusion criteria

Exclusion criteria: Diabetic patients Immunosuppressive patients Pregnant ladies

Design outcomes

Primary

Measure	Time frame
The size of oral lichen planus lesions. Timepoint: Measurement of oral lichen planus lesion size will be performed at the beginning of the study (before the intervention begins) and 1, 2, and 3 months later. Method of measurement: The size of the waste will be measured with a ruler (unit: centimeters).	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAshid Mohamed

Tehran University of Medical Sciences

asheed.almohammadi94@gmail.com+98 910 752 7437

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026