Poor ovarian response. Ovarian dysfunction
Conditions
Interventions
Intervention 1: Intervention Group: Patients in this group, in addition to receiving standard treatment (described below), will receive growth hormone (Somatotropin) from SinaGen Iran at a dose of 2.5
Sponsors
Sanandaj University of Medical Sciences
Eligibility
Sex/Gender
Female
Inclusion criteria
Inclusion criteria: The population is women with poor ovarian response who have referred to the infertility clinic of Besat Hospital and a private infertility center for an in vitro fertilization cycle. The inclusion criteria in this study are based on the patient-centered strategy segmentation including personalization of the number of eggs. Patients at levels 3 and 4 of this criterion are included in the study. Group 1 - Level 3 - Patients under 35 years of age with poor ovarian reserve parameters (antral follicle count less than 5 or anti-Müllerian hormone less than 1.2) (predicted) Group 2 - Level 4 - Patients over 35 years of age with poor ovarian reserve parameters (predicted)
Exclusion criteria
Exclusion criteria: Hydrosalpinx, congenital uterine abnormalities and/or endometrial disease such as tuberculosis or hyperplasia. Basal follicle-stimulating hormone level (FSH) greater than or equal to 15 units per liter (IU/L). Underlying diseases such as polycystic ovary syndrome and endometriosis. Infertility due to male causes Patients who have not undergone embryo transfer after more than six months of embryo freezing.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Number of follicles. Timepoint: It is checked for fertility on the third day of the cycle and on day 12. Method of measurement: Ultrasound of the uterus and appendages.;Number of eggs. Timepoint: It is checked for fertility on the third day of the cycle and on day 12. Method of measurement: Ultrasound of the uterus and appendages.;Egg quality. Timepoint: It is checked for fertility on the third day of the cycle and on day 12. Method of measurement: Ultrasound of the uterus and appendages.;Fertilization rate. Timepoint: It is checked for fertility on the third day of the cycle and on day 12. Method of measurement: Ultrasound of the uterus and appendages.;Egg grading. Timepoint: It is checked for fertility on the third day of the cycle and on day 12. Method of measurement: Ultrasound of the uterus and appendages.;Embryo quality. Timepoint: It is checked for fertility on the third day of the cycle and on day 12. Method of measurement: Ultrasound of the uterus and appendages.;Achieving fertility. Timepoint: The BHCG test is checked for fertility on day. Embryo transfer will also be performed on day 3 of the cycle. Method of measurement: Achieving fertility on day 12 of the IVF cycle is measured by checking the level of beta-human chorionic gonadotropin (BhCG) hormone in the blood via a blood test. Additionally, a control ultrasound (TVS) is performed on day 8 of the cycle by a radiologist to check the number of follicles. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactNeda Vaziri
Sanandaj University of Medical Sciences
Outcome results
None listed