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Investigating and comparing the effects of sertraline and buspirone on anxiety in children and adolescents with attention deficit hyperactivity disorder

Investigating and comparing the effects of sertraline and buspirone on anxiety in children and adolescents aged 6 to 17 years with attention deficit hyperactivity disorder

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20241207063978N1
Enrollment
88
Registered
2025-01-18
Start date
2025-01-20
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Attention-deficit hyperactivity disorders. Condition 2: Generalized anxiety disorder. Attention-deficit hyperactivity disorders Generalized anxiety disorder

Interventions

Intervention 1: Intervention group: The first intervention group receives methylphenidate (Ritalin) and buspirone. Methylphenidate (Ritalin) is initially given at a dose of 0.3 mg per kilogram of body

Sponsors

Hamedan University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 17 Years

Inclusion criteria

Inclusion criteria: Consent to participate in the study by parents Age 6 to 17 years Having ADHD and anxiety at the same time, based on DSM-5 criteria and the opinion of a pediatric psychiatrist

Exclusion criteria

Exclusion criteria: Presence of psychotic spectrum disorders Presence of intellectual disability Presence of autism spectrum disorders Severe physical illnesses

Design outcomes

Primary

MeasureTime frame
Symptoms of attention deficit hyperactivity disorder. Timepoint: At the beginning of the study and 8 weeks after starting the drug. Method of measurement: Conners parent rating scale questionnaire.;Anxiety symptoms. Timepoint: At the beginning of the study and 8 weeks after starting the drug. Method of measurement: The Spence Children's Anxiety Scale – Parent.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMehran Hajiloo

Hamedan University of Medical Sciences

webda@umsha.ac.ir+98 31310000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026