Septic shock. I95
Conditions
Interventions
Intervention 1: The intervention group consists of children aged from one month to 18 years who are admitted to the paediatric intensive care unit (PICU) of Mofid Hospital, which is affiliated with Sh
Sponsors
Shahid Beheshti University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Months to 18 Years
Inclusion criteria
Inclusion criteria: Admission to the Intensive Care Unit (ICU) The present study examines children diagnosed with vasodilatory shock according to the established criteria. In the Uscom study, a cardiac index greater than 2.5 was observed.
Exclusion criteria
Exclusion criteria: It is imperative that the withdrawal of parental consent is actioned. The potential for harm to the child during the investigative process must be considered. The cardiac index in the USCOM population is lower than 2.5
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison of the effects of vasopressin versus norepinephrine on shock symptoms based on its manifestations. Timepoint: The present study will examine the effects of vasopressin on shock symptoms at the study's commencement, prior to the administration of any drugs, and subsequently on a daily basis. Method of measurement: The present study investigates the use of the Ultrasound Cardiac Output Monitor (USCOM™). | — |
Secondary
| Measure | Time frame |
|---|---|
| The present study will compare the effects of vasopressin and norepinephrine on kidney function. Timepoint: Following admission and a 48-hour period. Method of measurement: Blood creatinine.;The present study will compare the effects of vasopressin and norepinephrine on urine volume. Timepoint: Following admission and a 48-hour period. Method of measurement: Urine volume.;The present study will compare the effects of vasopressin and norepinephrine on mortality. Timepoint: The following observations were made during the patient's hospitalisation, which lasted up to 28 days. Method of measurement: The following questionnaire must be completed.;The present study will compare the effects of vasopressin and norepinephrine on peripheral vascular resistance. Timepoint: Admission to the facility is accompanied by the requirement for daily monitoring. Method of measurement: The ultrasound cardiac output monitor is a piece of medical equipment used to measure the volume of blood ejected from the heart with each heartbeat.;The present study will compare the effects of vasopressin and norepinephrine on heart rate. Timepoint: Admission to the facility is accompanied by the requirement for daily monitoring. Method of measurement: Monitoring.;The present study will compare the effects of vasopressin and norepinephrine on blood pressure. Timepoint: Admission to the facility is accompanied by the requirement for daily monitoring. Method of measurement: Monitoring.;A comparison is made of the effects of vasopressin and norepinephrine on liver enzymes. Timepoint: Following admission and a 48-hour period. Method of measurement: The following essay will explore the subject of liver enzymes in the blood.;The present study will compare the effects of two different pharmaceutical agents, vasopressin and norepinephrine, on the duration of hospitalisation. Timepoint: Admission to the facility is accompanied by the requirement for daily monitoring. Method of measurement: The following questio | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactmasumeh Hashemi
Shahid Beheshti University of Medical Sciences
Outcome results
None listed