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Investigating the Relationship between Dermatoscopic Patterns and Response Rates in Mesotherapy of Melasma with Tranexamic Acid Ampoule

Investigating the Relationship between Dermatoscopic Patterns and Response Rates in Mesotherapy of Melasma with Tranexamic Acid Ampoule

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20241204063946N1
Enrollment
45
Registered
2024-12-29
Start date
2025-02-19
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Melasma. Diseases of the Skin and Subcutaneous Tissue

Interventions

Intervention group:The intervention Group Includes 45 Patients between the ages of 18 and 60 with Melasma. At the Beginning of the Study, for each Patient, in addition to Demographic information, incl

Sponsors

Iran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: People Aged 18 to 60 with a Diagnosis of Melasma

Exclusion criteria

Exclusion criteria: Any Melasma Treatment within the 1 Month ago Having Contraindications for the Use of Tranexamic Acid Having Psychiatric Diseases that May Affect the Study Process Lack of Informed Consent to Participate in the Study No Possibility of Regular Visit and Follow-up Having an Underlying Disease Related to Melasma

Design outcomes

Primary

MeasureTime frame
Melasma Severity based on Melasma Score. Timepoint: Three sessions of Mesotherapy with an Ampoule of Tranexamic Acid are Performed at the Melasma Site with an interval of Two Weeks, and the Patient is Evaluated 2 weeks after the Completion of the Treatment. Method of measurement: Modified Melasma Area and Severity Index.;Melasma. Timepoint: Three sessions of Mesotherapy with an Ampoule of Tranexamic Acid are Performed at the Melasma Site with an interval of Two Weeks, and the Patient is Evaluated 2 weeks after the Completion of the Treatment. Method of measurement: Physician Global Assessment Score.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactJangizahi Salman

Iran University of Medical Sciences

rasoolhospital@iums.ac.ir+98 21 6435 1000

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026