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The role of preoperative administration of oral Montelukast on post-operative pain following Groin surgery

The role of preoperative administration of oral Montelukast on post-operative pain following Groin surgery

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20241204063937N1
Enrollment
50
Registered
2025-01-10
Start date
2025-01-20
Completion date
Unknown
Last updated
2025-02-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Inguinal hernia. Condition 2: Scrotal varices. Inguinal hernia Scrotal varices

Interventions

Intervention 1: Two hours before the operation, patients in the intervention group will receive 10 mg Montelukast tablets by the student. Intervention 2: Patients will receive an ineffective placebo p

Sponsors

Mashhad University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: BMI lesser than 30 Candidate patients for varicocele surgery and inguinal hernia repair In the classification of the American Society of Anesthesiologists, ASA I, II.

Exclusion criteria

Exclusion criteria: Patients with a history of taking painkillers or nerve drugs in the last month Patients with a history of addiction or mental health problems Patients with any history of drug sensitivity Severe sinusitis Mental problems

Design outcomes

Primary

MeasureTime frame
The amount of pain after the operation in the first 24 hours. Timepoint: during 1, 3, 6, 12, 18 and 24 hours. Method of measurement: Using the VAS (Visual Analogue Scale) index, it will be recorded from 0 to 10.;The need for auxiliary pain medication and the amount of narcotic used by each patient. Timepoint: The duration of the administration of the first painkiller after the operation (based on minutes). Method of measurement: Average consumption of painkillers (morphine) after surgery (based on milligrams).

Secondary

MeasureTime frame
The need for auxiliary analgesics and additional doses of analgesics. Timepoint: in the 24 hours after the operation. Method of measurement: Amount of milligrams of Morphine.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMohammad alipour

Mashhad University of Medical Sciences

alipourm@mums.ac.ir+98 51 3801 2612

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026