Evaluation of the PRK and TransPRK surgery effect on retinal vessels

Microvascular changes of macula and optic nerve head after the PRK and TransPRK surgery: A clinical trial

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20241203063929N1

Enrollment

Registered

2025-01-10

Start date

2025-02-18

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Condition 1: Myopia. Condition 2: Hypermetropia. Condition 3: Refractive Errors. Myopia Hypermetropia Disorders of refraction and accommodation

Interventions

Intervention 1: Intervention group: PRK procedure - In this group, patients are included according to the specified criteria and undergo surgery using the PRK (photorefractive keratectomy) method. Thi

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients with refractive error appropriate for PRK or TransPRK procedure

Exclusion criteria

Exclusion criteria: Retinal pathologies affecting the vision, such as diabetic or hypertensive retinopathy Ocular pathologies like cataract, glaucoma, KCN, or corneal dystrophies History of ocular major trauma History of uveitis History of other ocular surgeries

Design outcomes

Primary

Measure	Time frame
Macular Deep plexus vascular density index. Timepoint: In addition to the preoperative examination, patients will have three visits after the operation: one week after the operation, one month after and three months after the surgery. Method of measurement: The vascular density data of the Deep retinal plexus at pre-op and post-op visits will be gathered from the OCTA device. The OCTA would be taken by a single expert technician.;Macular Superficial plexus vascular density index. Timepoint: In addition to the preoperative examination, patients will have three visits after the operation: one week after the operation, one month after and three months after the surgery. Method of measurement: The vascular density data of the Superficial retinal plexus at pre-op and post-op visits will be gathered from the OCTA device. The OCTA would be taken by a single expert technician.;Optic nerve head vascular density index. Timepoint: In addition to the preoperative examination, patients will have three visits after the operation: one week after the operation, one month after and three months after the surgery. Method of measurement: The vascular density data of the Optic nerve head at pre-op and post-op visits will be gathered from the OCTA device. The OCTA would be taken by a single expert technician.	—

Measure

Time frame

Macular Deep plexus vascular density index. Timepoint: In addition to the preoperative examination, patients will have three visits after the operation: one week after the operation, one month after and three months after the surgery. Method of measurement: The vascular density data of the Deep retinal plexus at pre-op and post-op visits will be gathered from the OCTA device. The OCTA would be taken by a single expert technician.;Macular Superficial plexus vascular density index. Timepoint: In addition to the preoperative examination, patients will have three visits after the operation: one week after the operation, one month after and three months after the surgery. Method of measurement: The vascular density data of the Superficial retinal plexus at pre-op and post-op visits will be gathered from the OCTA device. The OCTA would be taken by a single expert technician.;Optic nerve head vascular density index. Timepoint: In addition to the preoperative examination, patients will have three visits after the operation: one week after the operation, one month after and three months after the surgery. Method of measurement: The vascular density data of the Optic nerve head at pre-op and post-op visits will be gathered from the OCTA device. The OCTA would be taken by a single expert technician.

—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmin Arasteh

Tabriz University of Medical Sciences

amin.arasteh1995@gmail.com+98 41 3658 0130

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026