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The effect of topical clove gel on hemodynamic parameters and pain caused by arterial blood sampling in mechanically ventilated patients hospitalized in intensive care units: a triple blind randomized clinical trial

The effect of topical clove gel on hemodynamic parameters and pain caused by arterial blood sampling in mechanically ventilated patients hospitalized in intensive care units: a triple blind randomized clinical trial

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20241202063914N1
Enrollment
80
Registered
2025-03-21
Start date
2025-03-21
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Changes in hemodynamic indices and pain caused by arterial blood sampling in patients undergoing mechanical ventilation..

Interventions

Intervention 1: Intervention group: In all patients, Allen's test will be performed as a necessary diagnostic test before taking ABG, and if there is a disturbance in the blood supply to the patients

Sponsors

Shahroud University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients on mechanical ventilation who have been intubated for at least 24 hours Over 18 years old Stable hemodynamic conditions without receiving medications affecting hemodynamics Obtaining a pain score of less than or equal to 2 according to the CPOT scale Obtaining a score of 4 on the Ramsay Sedation Scale The need to perform arterial blood gas tests as ordered by the doctor

Exclusion criteria

Exclusion criteria: Skin damage at the radial artery site (wounds, burns, edema, scars, local infection, redness, and inflammation) Sensorimotor disorder in the upper limb Need for emergency ABG Allergy to clove gel Failure of the first attempt at arterial blood sampling

Design outcomes

Primary

MeasureTime frame
Pain score in the "Critical Care Pain Observation Tool" questionnaire. Timepoint: Pain score measurement during arterial sampling (when the needle is in the artery), 5 minutes, and 20 minutes after the needle is removed from the artery. Method of measurement: "Critical Care Pain Observation Tool" questionnaire.;Heart rate. Timepoint: Measuring the patients' heart rate in four stages: 5 minutes before the needle enters the artery, during sampling (when the needle is inside the artery), 5 minutes and 20 minutes after the needle leaves the artery. Method of measurement: Measurement with a "monitoring device" and recording in the hemodynamic indicators checklist.;Systolic and diastolic blood pressure levels. Timepoint: Measuring patients' systolic and diastolic blood pressure in four stages: 5 minutes before the needle enters the artery, during sampling (when the needle is inside the artery), 5 minutes and 20 minutes after the needle leaves the artery. Method of measurement: Measurement with a "monitoring device pressure gauge" and recording in the hemodynamic indicators checklist.;Blood oxygen saturation level. Timepoint: Measuring patients' blood oxygen saturation in four stages: 5 minutes before the needle enters the artery, during sampling (when the needle is inside the artery), 5 minutes and 20 minutes after the needle leaves the artery. Method of measurement: Measurement with a "pulse oximeter monitoring device" and recording in the hemodynamic indicators checklist.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMonire Kahne

Shahroud University of Medical Sciences

kahneimonireh@shmu.ac.ir+98 23 3220 1821

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026