Ovarian dysfunction. Ovarian dysfunction
Conditions
Interventions
Intervention 1: Intervention Group (PRP Group): Receives a single session of intraovarian injection of autologous Platelet-Rich Plasma (PRP) using the Royagen Kit:- Substance Name: Autologous Platelet
Sponsors
Avicenna research institute
Eligibility
Sex/Gender
Female
Age
20 Years to 39 Years
Inclusion criteria
Inclusion criteria: 1. Women aged 20-39 years Diagnosed with diminished ovarian reserve (low AMH and low AFC) Undergoing ICSI
Exclusion criteria
Exclusion criteria: Women with severe uterine abnormalities. Presence of systemic diseases affecting ovarian function. Refusal to participate in follow-up sessions.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Blood FSH hormone level. Timepoint: Before and after the intervention. Method of measurement: Blood FSH measurement kit.;Embryo quality. Timepoint: after treatment. Method of measurement: observation with a microscope. | — |
Primary
| Measure | Time frame |
|---|---|
| Antral fullicular count. Timepoint: Before and after inteventaion. Method of measurement: Ultrasound.;Anti mullerian hormon. Timepoint: Before and after intervention. Method of measurement: Special kit for checking hormones in blood.;Number of mature oocytes. Timepoint: Before and after intervention. Method of measurement: microscope.;Pregnancy. Timepoint: After treatment. Method of measurement: Beta HCG hormone in the blood. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Soheila Arefi
Avicenna Research Institute
Outcome results
None listed