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Investigating the effect of melatonin on the success of intrauterine insemination cycles

The study of the effect of melatonin on chemical pregnancy rates and the success of intrauterine insemination (IUI) cycles in infertile women

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20241122063802N3
Enrollment
60
Registered
2025-09-23
Start date
2025-09-23
Completion date
Unknown
Last updated
2025-10-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infertility. Female infertility

Interventions

Intervention 1: Intervention group: After initial evaluations by the physician, a baseline vaginal ultrasound of the uterus and ovaries will be performed on days 1 to 3 of the menstrual cycle using an

Sponsors

Tabriz University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Infertility within the last two years having partners with normal spermogram having normal hysterosalpingography or at least one open fallopian tube in hysterosalpingography

Exclusion criteria

Exclusion criteria: Having underlying endocrine diseases use of hormonal drugs in the past three months insufficient ovarian response having ovarian hyperstimulation syndrome use of sleeping medications having respiratory diseases that cause sleep disorders use of supplements containing melatonin in the past three months

Design outcomes

Primary

MeasureTime frame
Number of Mature Follicles in Women. Timepoint: Days 1 to 3 of the menstrual cycle (at the beginning of the study) and on the 10th day of the menstrual cycle. Method of measurement: Ultrasonography.;Chemical Pregnancies. Timepoint: 14 days after IUI. Method of measurement: hCG-B blood test.;Endometrial Thickness. Timepoint: Days 1 to 3 of the menstrual cycle (at the beginning of the study) and on the 10th day of the menstrual cycle. Method of measurement: Ultrasonography.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactReza Sattarpour

Tabriz University of Medical Sciences

rezasattarpour.tums@gmail.com+98 41 3553 9161

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026