Central Catheter Dialysis-Related Infections. Infection and inflammatory reaction due to other cardiac and vascular devices, implants and grafts
Conditions
Interventions
Intervention 1: Intervention group: In this group, 2% chlorhexidine in 70% alcohol will be administered to individuals. Following each dialysis session, prior to catheter insertion, this solution wil
Sponsors
Qazvin University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Informed consent obtained Patients aged 18 years and older Patients on dialysis with a central venous catheter Ability and willingness to participate in the study and adhere to treatment protocols
Exclusion criteria
Exclusion criteria: Acute or chronic medical conditions that, in the opinion of the Principal Investigator (PI), may interfere with the assessment of the efficacy and/or safety of the study drug Patients who have not received antibiotic treatment for a proven catheter infection in the past month Patients who have not been treated with mupirocin or chlorhexidine in the past month Patients with a history of previous severe allergic reactions or known drug allergies to any of the study treatments Patients with a fistula or a temporary catheter (Shaldon catheter) Patients undergoing routine dialysis for end-stage renal disease (ESRD) who have been hospitalized for any reason
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The rate of central venous catheter infection in dialysis patients. Timepoint: Measurement of infection rate in the second week, third week, fourth week, second month, third month, fourth month, fifth month, and sixth month. Method of measurement: Positive blood culture results and/or fever above 38 degrees Celsius, or hypothermia below 36.5 degrees Celsius during dialysis, and/or cellulitis (swelling, warmth, redness, or purulent discharge around the central catheter). | — |
Secondary
| Measure | Time frame |
|---|---|
| Determining Length of Hospital Stay Due to Central Venous Catheter Infection in Three Groups. Timepoint: Second week, third week, fourth week, second month, third month, fourth month. Method of measurement: Patient Record.;Determining Medication Consumption Behavior in Intervention and Control Groups. Timepoint: Checklist. Method of measurement: Second week, third week, fourth week, second month, third month, fourth month.;The determination of changes in depression in two groups: intervention and control. Timepoint: Second week, third week, fourth week, second month, third month, fourth month. Method of measurement: Patient Health Questionnaire-2 (PHQ-2).;The determination of changes in anxiety in two groups: intervention and control. Timepoint: Second week, third week, fourth week, second month, third month, fourth month. Method of measurement: Generalized Anxiety Disorder 2-item (GAD-2). | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAmin
Qazvin University of Medical Sciences
Outcome results
None listed