Studying the effect of minocycline on the prognosis of patients with intracerebral hemorrhage

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20241118063757N1

Enrollment

Registered

2026-02-10

Start date

2026-02-20

Completion date

Unknown

Last updated

2026-06-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Nontraumatic intracerebral hemorrhage. Nontraumatic intracerebral hemorrhage

Interventions

Intervention 1: Intervention group: The intervention group will receive minocycline in addition to the common treatment for intracranial hemorrhage.The initial dose of minocycline will be 200 mg admin

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Patients with intracerebral hemorrhage not due to trauma Patients aged 18 to 80 year

Exclusion criteria

Exclusion criteria: Need to surgical hematoma evacuation Allergic to tetracycline antibiotics Pregnancy Liver failure Coagulation disorders (including platelet count below 75,000 and INR above 1.4) A Glasgow Coma Scale (GCS) of 5 or lower

Design outcomes

Primary

Measure	Time frame
Cerebral hemorrhage absorption rate. Timepoint: Before and 10 days after the intervention. Method of measurement: CT scan.;Degree of disability. Timepoint: Before and 90 days after the intervention. Method of measurement: Modified Rankin Scale (mRS).	—

Secondary

Measure	Time frame
Mortality. Timepoint: 90 days after intervention. Method of measurement: Medical record or telephone follow-up.;Hospitalization duration. Timepoint: 90 days after intervention. Method of measurement: Medical record.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Mohammadreza Amiri Nikpour

Oroumia University of Medical Sciences

reza.nikpor@gmail.com+98 44 3345 7286

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Jun 11, 2026