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Study and comparison of anesthetic gels of jujube extract, tarragon extract, combination of tarragon and jujube extract, lidocaine and gel without anesthetic agent, on reducing the pain caused by needle insertion during the inferior alveolar nerve block anesthesia injection.

Study and comparison of anesthetic gels of jujube extract, tarragon extract, combination of tarragon and jujube extract, lidocaine and gel without anesthetic agent, on reducing the pain caused by needle insertion during the inferior alveolar nerve block anesthesia injection.

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20241115063712N1
Enrollment
100
Registered
2025-04-14
Start date
2024-12-05
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain caused by needle insertion during anesthesia injection.

Interventions

Intervention 1: Anesthetic gel containing tarragon extract: Made by the Faculty of Pharmacy, Mazandaran University of Medical Sciences, 3% concentration, extracted from tarragon leaf extract and proto

Sponsors

Mazandaran University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 60 Years

Inclusion criteria

Inclusion criteria: People are systemically healthy according to ASA classification 1 and 2 the GHQ-28 General Health Questionnaire, whose validity and reliability have been confirmed, is used to equate people psychologically. It is necessary not to have a history of allergy to anesthetics and not to use drugs affecting people's perception of pain. People without active infection in the injection area People volunteers will participate in the research plan.

Exclusion criteria

Exclusion criteria: A) Age below 20 years and above 60 years b) Pregnant women c) Presence of pain, inflammation and infection at the injection site d) Users of any medication that has altered their perception of pain, including painkillers and antidepressants

Design outcomes

Primary

MeasureTime frame
Pain level score in Visual Analogue Scale. Timepoint: One time, 3 minutes after injection. Method of measurement: Visual Analogue Scale.—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Hossein Moddabi

Mazandaran University of Medical Sciences

a.moaddabi2@gmail.com+98 11 3340 5474

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026