Acute brain injury patients on ventilators. Diffuse traumatic brain injury
Conditions
Interventions
Intervention 1: Intervention group1: In the PEEP ZEEP group, the ventilator's PEEP level is increased to 10 cmH2O, during which patients receive 5 respiratory cycles. Subsequently, the ventilator's PE
Sponsors
Arak University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Permission of the patient's guardian to participate in the research At least 2 days of hospitalization in the intensive care unit Patients with stable hemodynamics Brain-injured patients on Synchronized Intermittent Mandatory Ventilation (SIMV) ventilation Mean arterial pressure (MAP) between 60 and 110 mmHg, heart rate less than 110 beats per minute, and oxygen saturation (SPO2) greater than 90% if the ventilator's inspiratory oxygen percentage was less than 60%. Absence of damage to organs and chest
Exclusion criteria
Exclusion criteria: Severe kidney dysfunction (urine output <30 cc/hour). Use of sedative drugs such as Midazolam, Propofol, and vasoactive (Dopamine and Dobutamine). Using muscle relaxants (such as Atracurium, Pancuronium). Use of antihypertensive drugs.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Amount of sputum suctioned. Timepoint: Measurement of the amount of sputum suctioned on two consecutive days at 10 am in both intervention groups immediately after the procedure. Method of measurement: Suction bottle with cc measuring scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Systolic blood pressure. Timepoint: Before the intervention (time zero), immediately after the intervention (time one), and one hour (time two), two hours (time three), and three hours (time four) after the intervention in intervention groups one and two. Method of measurement: Blood pressure monitor with mmHg scale.;Arterial blood oxygen. Timepoint: Before the intervention (time zero), immediately after the intervention (time one), and one hour (time two), two hours (time three), and three hours (time four) after the intervention in intervention groups one and two. Method of measurement: SAADAT monitor device with erythrocyte/percent saturation scale.;Pulse rate. Timepoint: Before the intervention (time zero), immediately after the intervention (time one), and one hour (time two), two hours (time three), and three hours (time four) after the intervention in intervention groups one and two. Method of measurement: SAADAT monitor device with pulse/minute scale.;Respiratory rate. Timepoint: Before the intervention (time zero), immediately after the intervention (time one), and one hour (time two), two hours (time three), and three hours (time four) after the intervention in intervention groups one and two. Method of measurement: SAADAT monitor device with R/minute scale.;Diastolic blood pressure. Timepoint: Before the intervention (time zero), immediately after the intervention (time one), and one hour (time two), two hours (time three), and three hours (time four) after the intervention in intervention groups one and two. Method of measurement: Blood pressure monitor with mmHg scale.;Level of consciousness. Timepoint: Before the intervention (time zero), immediately after the intervention (time one), and one hour (time two), two hours (time three), and three hours (time four) after the intervention in intervention groups one and two. Method of measurement: Glasgow Coma Scale. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactBehnam Kandi
Arak University of Medical Sciences
Outcome results
None listed