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"Investigation of the Effects of Using a Dead Space Respiratory Volume Expander in Patients with Major Depressive Disorder.

"Investigation of the Effects of Using a Dead Space Respiratory Volume Expander System on Biological, Psychological, and Cognitive Stress Indicators in Patients with Major Depressive Disorder.

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20241113063695N1
Enrollment
50
Registered
2024-12-03
Start date
2024-12-21
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression.

Interventions

Intervention 1: Intervention Group 1: In this group, participants wear masks and breathe for 5 minutes daily. Intervention 2: Intervention group 2: In this group, participants wear masks and breathe

Sponsors

Bagheiat-allah University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 50 Years

Inclusion criteria

Inclusion criteria: The individual must have major depressive disorder. The individual must be at least 18 years old. The individual must not be older than 50 years The individual must not use addictive substances. The individual's Body Mass Index (BMI) must be between 20 and 30 The individual must not have inflammatory diseases. The individual must not have infectious diseases. The individual must not have diabetes. The individual must not have cardiovascular diseases.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

MeasureTime frame
Brain-Derived Neurotrophic Factor (BDNF). Timepoint: The first day, the 15th day and the 30th day. Method of measurement: Blood through the ELISA Reader: A device for measuring the optical density of samples in ELISA tests and providing qualitative or quantitative results.;Tumor Necrosis Factor Alpha (TNF-a). Timepoint: The first day, the 15th day and the 30th day. Method of measurement: Blood through the ELISA Reader: A device for measuring the optical density of samples in ELISA tests and providing qualitative or quantitative results.;Cortisol. Timepoint: The first day, the 15th day and the 30th day. Method of measurement: Blood through the ELISA Reader: A device for measuring the optical density of samples in ELISA tests and providing qualitative or quantitative results.;Inflammation System. Timepoint: The first day, the 15th day and the 30th day. Method of measurement: Blood through the ELISA Reader: A device for measuring the optical density of samples in ELISA tests and providing qualitative or quantitative results.;Cognitive abelities. Timepoint: The first day, the 15th day and the 30th day. Method of measurement: PASSAT Test: A test that measures cognitive abilities, including memory, attention, and cognitive fatigue.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactHedayat Sahraee

Bagheiat-allah University of Medical Sciences

hsahraei1343@gmail.com+98 912 419 0732

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026