Patients who suffered vascular complications following hyaluronic acid filler injection.
Conditions
Interventions
Intervention 1: Intervention group: To the patients who are placed in the hyaluronidase group with a high dose ,1500 units of hyaluronidase will inject with a needle, two hours later another 1500 unit
Sponsors
Tehran University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: Vascular complication following hyaluronic acid filler injection in the face area Occurrence of symptoms related to vascular complications (such as blanching, severe and sudden pain, Livedo reticularis, prolongation of capillary filling, ischemia and necrosis)
Exclusion criteria
Exclusion criteria: Injection of fillers other than hyaluronic acid Injection in areas other than the face The patient's sensitivity to hyaluronidase Hyaluronidase injection before going to the hospital Patient dissatisfaction The patient's need for additional treatments compared to research
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Any skin effects that remain from the initial lesion, such as scars, hypopigmentation, hyperpigmentation. Timepoint: Follow-up of patients in both groups is evaluated at 24 hours, 48 ??hours, one week, one month, and three months after the injection. Method of measurement: The clinical outcome is considered as Favorable outcome, Borderline outcome, Unfavorable outcome. Favorable outcome is the complete healing of the lesion and wound without leaving any scars or hypohyperpigmentation. Borderline outcome includes the complete healing of the lesion without leaving a scar with hypohyperpigmentation and Unfavorable outcome is the formation of a scar regardless of other symptoms. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactHamidreza Mahmoudi
Tehran University of Medical Sciences
Outcome results
None listed