Skip to content

Comparing the effect of probiotic product with fluoride mouthwash on Streptococcus mutans saliva

Comparison of the effect of the probiotic product Lactogum with fluoride mouthwash on the population of Streptococcus mutans in the saliva of Birjand dentistry students

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20241111063674N1
Enrollment
50
Registered
2024-11-29
Start date
2024-11-09
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Streptococcus mutans population of saliva.

Interventions

Intervention 1: Intervention group: one lozenge is placed in the mouth every night before going to bed after performing routine oral hygiene procedures (brushing and flossing) and allowing it to compl

Sponsors

Birjand University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: No use of probiotic products and systemic or topical antibiotics and corticosteroids during the last 4 weeks and at the time of the study No active dental infections No allergy to probiotic products or fluoride mouthwash

Exclusion criteria

Exclusion criteria: Being out of reach of people for any reason at the time of conducting the study Taking systemic or topical antibiotics and corticosteroids within 4 weeks before the start of the study and at the time of conducting the study Being allergic to probiotic products or fluoride mouthwash Fluoride therapy during the last 4 weeks Consumption of probiotic products during the last 4 weeks Presence of active dental infections

Design outcomes

Primary

MeasureTime frame
Changes in salivary Streptococcus mutans population. Timepoint: Before the start of the intervention and 7 days after the start of the intervention. Method of measurement: Collecting unstimulated saliva samples and counting the number of Streptococcus mutans colonies.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAmir Hassanpour

Birjand University of Medical Sciences

amir0155353762@gmail.com0082132853564

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026