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Comparing the effect of dexmetedomidine and remifentanil on controlled hypotension in patients undergoing general anesthesia candidates for spine surgery

Comparing the effect of dexmetedomidine and remifentanil on controlled hypotension in patients undergoing general anesthesia candidates for spine surgery

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20241108063640N2
Enrollment
70
Registered
2024-11-15
Start date
2024-12-20
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Adult patients with ASA I-II status undergoing spine surgery under general anesthesia.

Interventions

Intervention 1: Intervention group: Dexmedetomidine group. Intervention 2: Intervention group: Fentanyl withdrawal group.

Sponsors

Oroumia University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: Inclusion criteria included adult patients with ASA I-II status undergoing spine surgery under general anesthesia Completion of the informed consent form for participating in the study

Exclusion criteria

Exclusion criteria: Patients who need emergency surgery Pregnant people Patients with a history of spine surgery History of opioid use Drug abuse or alcohol addiction History of neurological diseases Neuromuscular or psychiatric (especially history of seizures or epilepsy) History of heart failure patients with cardiac bradycardia Long-term and chronic use of pain relievers, including cyclooxygenase 2 inhibitorsPatients with unpredictable events such as severe bleeding

Design outcomes

Primary

MeasureTime frame
Systolic and diastolic blood pressure control. Timepoint: (before induction), t1 (after induction), t2 (after incision), t3 (15 minutes after surgery), t9 (90 minutes after surgery), R0 (entering the recovery room) and R30 (30 minutes after from entering the recovery room). Method of measurement: by a non-invasive sphygmomanometer for anesthesia monitoring.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr.Hadi Hooshyar

Oroumia University of Medical Sciences

hooshyarhadi@gmail.com+98 44 3346 9931

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026