the effect of Gnrh agonist with and without letrozole on the success of FET cycles in infertile patients with endometriosis

Comparison of pregnancy rate following frozen embryo transfer in two methods of endometrial preparation using Gnrh agonist together with letrozole and Gnrh agonist alone in infertile patients with endometriosis

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20241107063631N2

Enrollment

Registered

2024-12-15

Start date

2024-11-12

Completion date

Unknown

Last updated

2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

endometriosis patient. Endometriosis of ovary

Interventions

Intervention 1: Intervention group: Treatment with GNRH agonist (decapeptyl ampoule with a dose of 3.75 mg intramuscularly (varian pharmed) along with letrozole 2.5 mg daily (from Iran Hormone Pharmac

Eligibility

Sex/Gender

Female

Age

21 Years to 40 Years

Inclusion criteria

Inclusion criteria: infertile patients with endometriosis referred to Taleghani Hospital 21-40 years old absence of severe male factor infertility absence of RIF absence of hydrosalpinx

Exclusion criteria

Exclusion criteria: severe male factor infertility RIF hydrosalpinx Patient dissatisfaction during treatment Presence of pathology in the endometrium

Design outcomes

Primary

Measure	Time frame
Clinical pregnancy. Timepoint: 4week after fet. Method of measurement: sonography.;Abortion. Timepoint: till (12week) gestational age. Method of measurement: sonography.;Chemical pregnancy. Timepoint: 2 & 4 week after fet. Method of measurement: laboratory kit.;Endometrial length. Timepoint: before fet. Method of measurement: sonography.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactSedighe Hosseini

Shahid Beheshti University of Medical Sciences

s_s_hoseini58@yahoo.com+98 21 2243 2560

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026