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Comparison of a single dose of Ibuprofen 400 mg and Fluoride gel on pain reduction in scaling and root planning pain

Comparing the effect of a systemic dose of Ibuprofen 400 mg with Fluoride gel in reducing scaling and root planning pain in patients with moderate to severe periodontitis

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20241106063620N1
Enrollment
100
Registered
2024-11-21
Start date
2024-12-14
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Moderate to severe periodontitis.

Interventions

Intervention 1: Intervention Group: Patients with moderate to severe periodontitis who are candidates for scaling and root planning treatment and refer to the Department of Periodontology at the Denta

Sponsors

Sanandaj University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with moderate to severe periodontitis referred to the Department of Periodontics Diseases of Kurdistan University of Medical Sciences

Exclusion criteria

Exclusion criteria: The presence of orthodontic brackets, the presence of movable prostheses, any use of sedatives or narcotics by the patient , patient's lack of cooperation , patient's lack of satisfaction. Individuals with gastritis and other digestive problems The patients who using a high dose of Warfarin, Metformin, Methotrexate and Furosemide are excluded from the group receiving Ibuprofen tablets and placed in the group receiving Fluoride gel. Individuals who are allergic to Fluoride gel are excluded from the group receiving Fluoride gel and are placed in the group receiving Ibuprofen tablets or placebo tablets. Patients requiring anesthesia during scaling and root planning due to experiencing severe pain and high levels of anxiety were excluded Patients who using of sedative drugs such as Diazepam, Clonazepam, Triazolam and Alprazolam and other sedative drugs are excluded from the study. Patients consuming sedatives or alcohol that reduces senses are excluded from the study Mothers during pregnancy and breastfeeding

Design outcomes

Primary

MeasureTime frame
The reduction amount pain , during the scaling procedure was 1.23% in patients receiving Fluoride gel and in patients receiving a single systemic dose of 400 mg Ibuprofen. Timepoint: 3 months. Method of measurement: Questionnaire VAS (Visual analog scale).

Countries

Iran (Islamic Republic of)

Contacts

Public Contactmohammad bahiraei

Sanandaj University of Medical Sciences

mohammad1997bahiraei@gmail.com+98 87 3324 4990

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026