Investigating the effect of insulin glargine injection timing on changes in blood sugar profile

Comparative investigation of the effect of bedtime and morning insulin glargine on glucose profile in diabetes mellitus type II patient

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20241105063603N1

Enrollment

Registered

2025-11-17

Start date

2023-03-21

Completion date

Unknown

Last updated

2025-12-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Diabetes, hypoglycemia, glargine. Type 2 diabetes mellitus with hypoglycemia

Interventions

This is a single-group study, and 40 patients with type 2 diabetes injected insulin glargine at night for three months, and after a three-month washout period, the same patients injected insulin durin

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Type 2 diabetes diagnosed for more than 3 years Type 2 diabetic patients treated with insulin glargine starting more than one year

Exclusion criteria

Exclusion criteria: Patients with type 1 diabetes Patients requiring an increase in insulin glargine dose Patients needing to start a new blood sugar control medication

Design outcomes

Primary

Measure	Time frame
Control of HbA1c. Timepoint: 90 days. Method of measurement: Blood test.;Control of fasting blood suger. Timepoint: 90 days. Method of measurement: blood test.;Control of 2hpp. Timepoint: 90 days. Method of measurement: blood test.	—

Countries

Iran (Islamic Republic of)

Contacts

Public Contactrazie malek mohammadi

Artesh University of Medical Sciences

r.malekmohammadi@gmail.com+98 21 4382 2449

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026