pyelonephritis. Acute nephritic syndrome with unspecified morphologic changes
Conditions
Interventions
Intervention 1: Dexamethasone o.15 mg/kg q6h and Ceftriaxone 80 mg/kg/day in intervention group for 4 days. Intervention 2: Control group: 80 mg/kg/day ceftriaxone and placebo ( normal saline) in con
Sponsors
Ghoum University of Medical Sciences
Eligibility
Sex/Gender
All
Age
1 Months to 14 Years
Inclusion criteria
Inclusion criteria: Children from 1 month to 14 years Children with first UTI in life Children with UTI have positive urine culture Children with clinical symptoms related to acute pyelonephritis (APN)
Exclusion criteria
Exclusion criteria: Endocrine diseases Immune deficiency diseases Cancer Known uropathy (ie known VUR, CAKUT and UTD) Patients with a second UTI during the study period Patients without evidence of acute pyelonephritis (APN)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Urinary IL6 and IL8 evaluate by ELISA. Timepoint: Before and after 4 months of treatment. Method of measurement: laboratory. | — |
Secondary
| Measure | Time frame |
|---|---|
| Renal scaring. Timepoint: before and 4 month after treatment. Method of measurement: isotope scan. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactFarzad Ahmadzadeh Fard
Ghoum University of Medical Sciences
Outcome results
None listed