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comparison of post cesarean wound infection with or without use of hydrogen peroxide during cesarean wound cleaning

comparison of post cesarean wound infection with or without use of hydrogen peroxide during cesarean wound cleaning

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20241104063588N2
Enrollment
204
Registered
2025-05-31
Start date
2024-01-01
Completion date
Unknown
Last updated
2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Post-cesarean wound infection and delayed wound healing are common complications following cesarean section. These conditions contribute to increased maternal morbidity, prolonged hospital stays, and higher healthcare costs. This study focuses on evaluating methods to reduce surgical site infections and promote faster wound recovery in postpartum women.. Infection of obstetric surgical wound

Interventions

Intervention 1: Intervention group: Intervention group: Participants received wound irrigation with 3% hydrogen peroxide solution immediately after cesarean section and before skin closure. The proced

Sponsors

Jinnah Postgraduate Medical Center (JPMC)
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 40 Years

Inclusion criteria

Inclusion criteria: Women aged between 18 and 40 years. Undergoing elective or emergency cesarean section. Gestational age greater than 36 weeks. Able and willing to provide informed consent. Agreed to attend postoperative follow-up visits for four weeks. No known allergy to hydrogen peroxide or normal saline. Hemodynamically stable after cesarean delivery.

Exclusion criteria

Exclusion criteria: Known hypersensitivity or allergy to hydrogen peroxide. Presence of chronic systemic diseases (e.g., chronic obstructive pulmonary disease, stroke, renal or hepatic impairment, malignancies). Patients with ongoing infections at the time of cesarean section. Immunocompromised individuals (e.g., HIV positive, on immunosuppressive therapy). Women with hemodynamic instability postoperatively. Patients with hematological disorders affecting wound healing. Inability to provide informed consent. Refusal or inability to attend follow-up visits for four weeks.

Design outcomes

Primary

MeasureTime frame
Incidence of post-cesarean wound infection, defined by clinical signs such as pus discharge, inflammation, deep tissue involvement, or hematoma requiring aspiration, assessed weekly for four weeks after surgery. Timepoint: 48 hours, 1 week, 2 weeks, 3 weeks, and 4 weeks after intervention. Method of measurement: Clinical examination using predefined criteria including presence of pus, redness, swelling, warmth, deep tissue involvement, or hematoma requiring aspiration, performed by trained healthcare professionals during follow-up visits.

Secondary

MeasureTime frame
Wound healing time, categorized as early (9 days), assessed weekly over a four-week postoperative period. Timepoint: 1 week, 2 weeks, 3 weeks, and 4 weeks after intervention. Method of measurement: Clinical assessment of wound healing by trained healthcare professionals, based on visual inspection and categorized as healed within 9 days, recorded during weekly follow-up visits.

Countries

Pakistan

Contacts

Public ContactDr Bisma

Jinnah Postgraduate Medical Centre

shaikhsahab553195@gmail.com+92 331 3032992

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026