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Investigating the effect of regular physical activities on the bacteria of the intestines of obese people after gastric surgery

Investigating the effect of regular physical activities on the abundance of some selected SCFA-producing bacteria in the intestines of obese people after gastric bariatric surgery

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
IRCT
Registry ID
IRCT20241103063587N1
Enrollment
45
Registered
2024-12-05
Start date
2024-12-10
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Obesity. Obesity due to excess calories

Interventions

The post-surgical rehabilitation protocol for patients undergoing surgery includes a structured exercise regimen designed to facilitate recovery. Initial Phase (Days 1-4) Walking: Patients start walki
and hip movements like abduction, adduction, extension, and flexion. Patients receive an educational booklet that outlines exercise instructions. Progress is assessed through m

Sponsors

university of tehran
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 50 Years

Inclusion criteria

Inclusion criteria: Absence of Unmanaged diabetes, poorly controlled hypertension, Major cardiovascular conditions, advanced pulmonary disease (COPD), Significant physical mobility restrictions, Serious neurological disorders that limit function Avoiding concurrent surgical procedures No previous weight loss surgery

Exclusion criteria

Exclusion criteria: The progression of musculoskeletal conditions and debilitating neurological disorders that impair an individual's ability to perform functional assessments The start of any medications or supplements that can influence body weight, including Appetite suppressants, Weight-loss supplements (except those specifically prescribed by the post-surgery care team), Cardiovascular medications The presence of cardiac implantable electronic devices (CIEDs), such as pacemakers, implantable cardioverter defibrillators (ICDs), or cardiac resynchronization therapy devices (CRT-Ds), which has been considered a contraindication for bioelectrical impedance analysis (BIA) due to concerns about potential electromagnetic interference A reluctance to maintain collaboration.

Design outcomes

Primary

MeasureTime frame
The impact of bariatric surgery and regular physical activity on the prevalence of Coprococcus bacteria in the gut microbiome of obese patients. Timepoint: Alteration in the prevalence of Coprococcus species within the intestinal microbiome, comparing baseline measurements to those taken three months after intervention. Method of measurement: Utilizing a specialized kit designed for extracting Deoxyribonucleic acid from fecal samples, followed by analysis using the real-time polymerase chain reaction technique.;The impact of bariatric surgery and regular physical activity on the prevalence of Roseburia bacteria in the gut microbiome of obese patients. Timepoint: Alteration in the prevalence of Roseburia species within the intestinal microbiome, comparing baseline measurements to those taken three months after intervention. Method of measurement: Utilizing a specialized kit designed for extracting Deoxyribonucleic acid from fecal samples, followed by analysis using the real-time polymerase chain reaction technique.;The impact of bariatric surgery and regular physical activity on the prevalence of Ruminococcus bacteria in the gut microbiome of obese patients. Timepoint: Alteration in the prevalence of Ruminococcus species within the intestinal microbiome, comparing baseline measurements to those taken three months after intervention. Method of measurement: Utilizing a specialized kit designed for extracting Deoxyribonucleic acid from fecal samples, followed by analysis using the real-time polymerase chain reaction technique.;The change in the abundance of the bacterial genus Alistipes in the gut microbiota of obese individuals after bariatric surgery and after regular physical activity. Timepoint: Alteration in the prevalence of Alistipes species within the intestinal microbiome, comparing baseline measurements to those taken three months after intervention. Method of measurement: Utilizing a specialized kit designed for extracting Deoxyribonucleic acid from fecal sam

Secondary

MeasureTime frame
The Effect of Regular Physical Activity on lipid profile changes in Obese Individuals after Bariatric Surgery. Timepoint: Changes in lipid profile before and 3 months after the intervention. Method of measurement: Utilizing Lipid control kits.;The Effect of Regular Physical Activity on Glucose Profile Changes in Obese Individuals After Bariatric Surgery. Timepoint: Changes in glucose profile before and 3 months after the intervention. Method of measurement: Utilizing glucose kits.;Impact of Regular Physical Activity on Fitness Test Outcomes in Post-Bariatric Surgery Patients with Obesity. Timepoint: Changes in physical fitness tests before and 3 months after the intervention. Method of measurement: Functional Capacity Assessment: Method: 12-Minute Walk Test (12MWT), Measurement: Distance covered in 12 minutes. Muscle Strength Evaluation: Method: One-Repetition Maximum (1RM) Tests, Focus: Lower limb muscles. Measurement: Number of repetitions completed. physical Activity Monitoring: Method: Personal Activity Logbook, Measurement: Self-reported activity levels and durations. Balance Assessment: Method: Standardized Balance Tests.;The Impact of Regular Physical Activity on Body Composition Changes in Post-Bariatric Surgery Patients with Obesity. Timepoint: Changes in anthropometric factors (weight, body mass index, and body fat percentage) before and 3 months after the intervention. Method of measurement: Utilization of a bioimpedance analysis device, a height measuring device with an accuracy of 1 millimeter, and a scale with an accuracy of 0.01 kilograms.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahdiyeh Zamankhanpour

University of Tehran

M.zamankhanpour@ut.ac.ir+98 21 8863 5891

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026