Non-alcoholic fatty liver disease. Fatty (change of) liver, not elsewhere classified
Conditions
Interventions
Intervention 1: For 12 weeks, garlic and curcumin tablets manufactured by Mehr and Mah Pharmaceuticals are prescribed to 40 people (Garlinovus tablets containing garlic extract (500 mg) and vitamins B
Sponsors
Mashhad University of Medical Sciences
Mehr and Mah Pharmaceutical Knowledge enterprise Company
Eligibility
Sex/Gender
All
Age
15 Years to 75 Years
Inclusion criteria
Inclusion criteria: Having AST and ALT above 33 in men and 25 in women Having at least one of the following: a- diabetes b- hyperlipidemia c- obesity Age 15 to 75 years old No consumption or no history of alcohol consumption No positive viral hepatitis serology (B,C,...) ANA or AMA tests, a1 antitrypsin, serum level of ceruloplasmin, level of ASMA antibodies and LKM1 and coagulation tests and serum albumin are normal. Absence of ferritin above 450 or 45% <IRON / TIBC The patient does not have coagulation disorders. Before the intervention, the patient should not have an acute or chronic disease that causes LFT (liver function tests) disorders. Before the study, the patient should take medication that has the potential to disrupt LFT. Presence of fatty liver in ultrasound
Exclusion criteria
Exclusion criteria: During the intervention, the patient suffers from an acute or chronic disease that causes a disturbance in LFT (liver function tests). The patient should take medication during the study that has the potential to disrupt LFT. Get pregnant during the study. The patient's unwillingness to continue cooperation during the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Amount of liver laboratory test. Timepoint: At the beginning of the study (before the start of the intervention) and 12 weeks after the start of taking garlic and curcumin tablets. Method of measurement: Fibro scan and laboratory tests. | — |
Secondary
| Measure | Time frame |
|---|---|
| Fibro scan changes. Timepoint: At the beginning of the study (before the start of the intervention) and 12 weeks after the start of taking garlic and curcumin tablets. Method of measurement: Fibroscan device. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAli Beheshtinamdar
Mashhad University of Medical Sciences
Outcome results
None listed