Obesity. Obesity due to excess calories
Conditions
Interventions
Intervention group: Bariatric surgery (sleeve), Regular physical activity, Bariatric surgery performed as a sleeve and is a type of weight loss surgery that can cause weight loss by removing part of t
Sponsors
The University of Tehran
Eligibility
Sex/Gender
All
Age
20 Years to 50 Years
Inclusion criteria
Inclusion criteria: Obese people who undergo gastric bariatric surgery (sleeve) Not having a history of uncontrolled diabetes, severe cardiovascular diseases, musculoskeletal limitations and limiting and severe neurological disorders, uncontrolled hypertension, severe chronic obstructive pulmonary diseases No concurrent surgery or history of previous weight loss surgery
Exclusion criteria
Exclusion criteria: Creating musculoskeletal problems and limiting neurological disorders that prevent functional tests Having alternative electrical devices such as pacemakers in the body that interfere with body composition analysis Starting medications that affect weight such as appetite suppressants and taking any other supplements (except supplements prescribed by the post-surgical follow-up team) and cardiovascular medications Taking antibiotics 2 months before sampling Unwillingness to continue cooperation
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Abundance of the bacterial genus Lactobacillus. Timepoint: At the beginning of the study (before starting the interventions) and three months after starting the interventions. Method of measurement: Using a Deoxyribonucleic acid extraction kit from stool by the real-time polymerase chain reaction method.;Abundance of the bacterial genus Bifidobacterium. Timepoint: At the beginning of the study (before starting the interventions) and three months after starting the interventions. Method of measurement: Using a Deoxyribonucleic acid extraction kit from stool by the real-time polymerase chain reaction method.;Abundance of the bacterial genus Faecalibacterium. Timepoint: At the beginning of the study (before starting the interventions) and three months after starting the interventions. Method of measurement: Using a Deoxyribonucleic acid extraction kit from stool by the real-time polymerase chain reaction method.;Abundance of the bacterial genus Akkermansia. Timepoint: At the beginning of the study (before starting the interventions) and three months after starting the interventions. Method of measurement: Using a Deoxyribonucleic acid extraction kit from stool by the real-time polymerase chain reaction method.;Abundance of the bacterial genus Bacteroides. Timepoint: At the beginning of the study (before starting the interventions) and three months after starting the interventions. Method of measurement: Using a Deoxyribonucleic acid extraction kit from stool by the real-time polymerase chain reaction method.;Abundance of the bacterial genus Prevotella. Timepoint: At the beginning of the study (before starting the interventions) and three months after starting the interventions. Method of measurement: Using a Deoxyribonucleic acid extraction kit from stool by the real-time polymerase chain reaction method.;Bacterial ratio of Prevotella to Bacteroides. Timepoint: At the beginning of the study (before starting the interventions) and three months after starting the interve | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in glucose homeostasis. Timepoint: At the beginning of the study (before starting the interventions) and three months after starting the interventions. Method of measurement: Through blood tests and glucose kit measurements.;Changes in anthropometric indicators including weight and body mass index. Timepoint: At the beginning of the study (before starting the interventions) and three months after starting the interventions. Method of measurement: Using a stadiometer, scale, and bioimpedance device.;Measuring functional capacity. Timepoint: At the beginning of the study (before starting the interventions) and three months after starting the interventions. Method of measurement: Using the walking test (MWT 12) in meters walked. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactParvaneh Ettefagh
The university of tehran, Faculty of Sports and Health Sciences
Outcome results
None listed