Study the effect of misoprostol and extra-amniotic infusion of saline combined with magnesium sulfate in cervical ripening

Comparison of three methods of misoprostol and extra-amniotic infusion of saline combined with magnesium sulfate and extra-amniotic infusion of saline combined with dexamethasone in cervical ripening

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

IRCT

Registry ID

IRCT20241103063573N1

Enrollment

100

Registered

2024-11-28

Start date

2024-11-05

Completion date

Unknown

Last updated

2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Preparing the cervix for labor induction. induction of labor

Interventions

Intervention 1: Intervention group: misoprostol. Intervention 2: Intervention group:Extra amniotic saline infusion (EASI) combined with magnesium sulfate. Intervention 3: Intervention group: Extra amn

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: term and post-term pregnant women

Exclusion criteria

Exclusion criteria: Women with identified anomalies of the uterus uterine cervix or possible uterine contractions Having uterine contractions previous cesarean sections

Design outcomes

Primary

Measure	Time frame
Induction to delivery interval. Timepoint: All three groups are continuously monitored for 12 hours, and every 2 hours the Bishop score is evaluated based on the examination of the patient's cervix with a minimum score of 0 and a maximum of 13 points. Method of measurement: checklist.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactZahra Ghavami

Ardabil university of medical sciences

zamaniantooba@gmail.com+98 45 3353 4742

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026