Comparison of remifentanil and dexmedetomedin in pain control after lumbar spine surgery.
Conditions
Interventions
Intervention 1: Intervention group: After anesthesia induction in a similar plan, patients will receive dexmedetomidine (Precedex) at a dose of 0.01 µg / kg per hour as an infusion. Intervention 2: In
Sponsors
Karaj University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: Age between 18 and 65 years Patient consent to participate in the study Candidates for lumbar surgery require general anesthesia History
Exclusion criteria
Exclusion criteria: Heart blocks such as atrial, intraventricular or sinus-atrial block Heart rate less than 50 or heart failure with ejection fraction less than 40% Epilepsy or convulsions Obstructive sleep apnea syndrome Patients with unpredictable events such as severe bleeding Pregnancy or breastfeeding drop in blood pressure
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The study "comparison of the effect of two drugs remifentanil and dexmedomedin in reducing pain after lumbar spine surgery" the primary outcome of pain reduction measured at different times. Timepoint: Measurement: during in recovery, 2 , 8 and 24 hours after the surgery , It is measured , in addition to pain control, secondary outcomes such as: nausea and vomiting are measured. Method of measurement: Questionnaire: Measuring the Visual Analogue Scale (VAS) and scoring the Ramsy Sedation Assessment Scale (RSAS) in compliance with research ethics and the approval of the ethics committee. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMaryam Mardani hossein abadi
Karaj University of Medical Sciences
Outcome results
None listed