Post-dural puncture headache is a headache that develops within 5 days after dural puncture which worsens in an upright position and improves with lying down and accompanied by neck stiffness, tinnitus, photophobia, and nausea.. Delivery by elective caesarean section
Conditions
Interventions
Intervention 1: Intervention group A:This group will receive 8mg and 600mg of intravenous ondansetron and paracetamol respectively. Intervention 2: Intervention group B will receive 8mg of intravenou
Sponsors
University of Nigeria Teaching Hospital,Enugu,Nigeria
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Booked patient at term attending antenatal care at the study centers. 18 – 40-year-old. ASA I and II parturients undergoing elective caesarean section under spinal anaesthesia.
Exclusion criteria
Exclusion criteria: Patients with known contraindication to spinal anaesthesia Allergy to the study drugs Patients with comorbidities like pregnancy induced hypertension, gestational diabetes mellitus, coronary artery disease or heart disease Patients taking drugs like selective serotonin receptor inhibitors (SSRIs) Patients converted into general anaesthesia
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcome measure will be the incidence of post dural puncture headache within 24 hours following caesarean delivery. Timepoint: At 6,12,18 and 24 hours post-caesarean section. Method of measurement: This will be assessed using the visual analogue scale. | — |
Secondary
| Measure | Time frame |
|---|---|
| Maternal complications (spinal anaesthesia induced hypotension, intra operative and post operative nausea and vomiting). Timepoint: 1 hour,6 hours,12 hours,18 hours,24 hours. Method of measurement: Blood pressure check and report of any incidence of nausea and vomiting.;Neonatal complications (Apgar scores at 1 and 5 min, the need for cardiopulmonary resuscitation and admission to the neonatal intensive care unit (NICU) during the first 24 hours after delivery will be assessed too). Timepoint: 1 minute,5 minutes, 24 hours. Method of measurement: APgar scoring and report of any incidence of the above interventions. | — |
Countries
Nigeria
Contacts
Public ContactDr . Ogwueleka, Chukwudubem Vitalis
University of Nigeria Teaching Hospital,Enugu,Nigeria
Outcome results
None listed