Lidocaine and adrenaline vs formalin -soaked gauze for vaginal packing after cervical biopsy for cervical cancer in Enugu Nigeria; A randomized controlled trial

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

IRCT

Registry ID

IRCT20241028063524N1

Enrollment

110

Registered

2024-11-04

Start date

2025-01-02

Completion date

Unknown

Last updated

2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Control of bleeding after cervical cancer biopsy. Malignant neoplasm of cervix uteri

Interventions

Intervention 1: Intervention group: Ten milliliters of 2% lidocaine and adrenaline will be used to soak the tip of gauze .The soaked tip of gauze will be used to pack the vagina after cervical biops

Eligibility

Sex/Gender

Female

Age

35 Years to 70 Years

Inclusion criteria

Inclusion criteria: Consenting women with suspected cervical cancer

Exclusion criteria

Exclusion criteria: Women who have cardiac abnormalities such as high blood pressure, heart failure, rheumatic heart diseases

Design outcomes

Primary

Measure	Time frame
Peri-operative blood loss. Timepoint: 1 hour,4 hours,8 hours,12 hours, 16 hours 20 hours and 24 hours. Method of measurement: Checking the vital signs ,the pads and the postoperative packed cell volume at 24 hours after cervical biopsy.	—

Secondary

Measure	Time frame
Need for blood transfusion. Timepoint: 1 hour,4 hours,8 hours,12 hours, 16 hours ,20 hours and 24 hours. Method of measurement: This will be determined based on the clinical condition of the participant and her postoperative packed cell volume.;Vaginal itching. Timepoint: 1 hour,4 hours,8 hours,12 hours, 16 hours ,20 hours and 24 hours. Method of measurement: The participant will be asked if she has vaginal itching .;Pain following the biopsy. Timepoint: 1 hour,4 hours,8 hours,12 hours, 16 hours ,20 hours and 24 hours. Method of measurement: The visual analogue scale will be used .;Cardiovascular adverse effects such as tachycardia, arrhythmia, hypertension, cerebrovascular accident and myocardial infarction. Timepoint: 1 hour,4 hours,8 hours,12 hours, 16 hours ,20 hours and 24 hours. Method of measurement: Checking the pulse rate, heart sounds, blood pressure and oxygen saturation.	—

Measure

Time frame

Need for blood transfusion. Timepoint: 1 hour,4 hours,8 hours,12 hours, 16 hours ,20 hours and 24 hours. Method of measurement: This will be determined based on the clinical condition of the participant and her postoperative packed cell volume.;Vaginal itching. Timepoint: 1 hour,4 hours,8 hours,12 hours, 16 hours ,20 hours and 24 hours. Method of measurement: The participant will be asked if she has vaginal itching .;Pain following the biopsy. Timepoint: 1 hour,4 hours,8 hours,12 hours, 16 hours ,20 hours and 24 hours. Method of measurement: The visual analogue scale will be used .;Cardiovascular adverse effects such as tachycardia, arrhythmia, hypertension, cerebrovascular accident and myocardial infarction. Timepoint: 1 hour,4 hours,8 hours,12 hours, 16 hours ,20 hours and 24 hours. Method of measurement: Checking the pulse rate, heart sounds, blood pressure and oxygen saturation.

—

Countries

Nigeria

Contacts

Public ContactDr . Obi Chinedu Kingsley

University of Nigeria Teaching Hospital,Enugu,Nigeria

chinedukobic@gmail.com+234 813 471 9913

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026