Comparative efficacy of bifonazole and clotrimazole in the treatment of pitryasis versicolor

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

IRCT

Registry ID

IRCT20241028063523N1

Enrollment

Registered

2024-11-06

Start date

2024-11-01

Completion date

Unknown

Last updated

2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pitryasis versicolor is a chronic cutaneous fungal infection caused by proliferation of lipophilic yeast (malassezia species) in stratum corneum.. Pityriasis versicolor

Interventions

Intervention 1: Clinically and mycologically confirmed cases of Pitryasis versicolor shall be divided into 2 groups. Group 1 and Group 2.

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: All patients who will have clinically pitryasis versicolor as per operational definition Patients within range of 18-60 years of age Willing to provide informed consent

Exclusion criteria

Exclusion criteria: Patients with local inflammatory of infectious disease at the site to be treated or who will be allergic to topical medication Previously treated patients Patients delevelop side effects during study

Design outcomes

Primary

Measure	Time frame
The primary outcome of the study will focus on mycological cure ( negative microscopy of fungal hyphae by potassium hydroxide mount). Timepoint: Patient will be assessed before intervention, at 2 weeks and 4 weeks after intervention. Method of measurement: Method used to assess mycological cure will be skin scrapping mount with potassium hydroxide( negative for fungal hyphae).;The primary outcome of the study will focus on alleviation of physical symptoms such as leision clearence ,erythema, pruritis, desqamation and absence of yellow floresence on wood's lamp examination. Timepoint: Patient will be assessed Before intervention,at 2 weeks and 4 weeks after intervention. Method of measurement: Method used to assess clinical cure will be wood's lamp examination(absence of clinical signs).	—

Measure

Time frame

The primary outcome of the study will focus on mycological cure ( negative microscopy of fungal hyphae by potassium hydroxide mount). Timepoint: Patient will be assessed before intervention, at 2 weeks and 4 weeks after intervention. Method of measurement: Method used to assess mycological cure will be skin scrapping mount with potassium hydroxide( negative for fungal hyphae).;The primary outcome of the study will focus on alleviation of physical symptoms such as leision clearence ,erythema, pruritis, desqamation and absence of yellow floresence on wood's lamp examination. Timepoint: Patient will be assessed Before intervention,at 2 weeks and 4 weeks after intervention. Method of measurement: Method used to assess clinical cure will be wood's lamp examination(absence of clinical signs).

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Secondary

Measure	Time frame
Tolerability of drugs by monitoring side effects. Timepoint: At 2 weeks and at 4 weeks. Method of measurement: i will measure clinical cure by woods lamp examination(absence of signs) and mycological cure by skin scrapping (negative for fungal hyphae) and side effects (if any).	—

Countries

Pakistan

Contacts

Public ContactDr Atiya Rahman

Armed forces Hospital, PNS Shifa

sanasaleem20694@gmail.com+92 21 48506540

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026