Hypotension following caesarean section. Hypotension
Conditions
Interventions
Intervention 1: Intervention group: Patients in the intervention group will receive 4 mg of ondansetron, manufactured by Tehran Chemie Company, in 8 cc of normal saline, manufactured by Samen Pharmace
Sponsors
Birjand University of Medical Sciences
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: Informed consent to enter the study ASA class 1 and 2 Term pregnancy, singleton pregnancy, and elective caesarean section Availability of desired information
Exclusion criteria
Exclusion criteria: Patients with brain trauma, febrile illness, spine problems, spinal anesthesia site infection, blood coagulation disorders, heart valve problems, especially aortic valve stenosis, and any chronic cardiovascular, kidney, and neuropsychiatric diseases. Suffering from preeclampsia or any type of hypertension during pregnancy Patients with high ICP or hypovolemic patients Drug addiction Allergy to local anesthetics or ondansetron Inability to position properly People with long QTc on ECG People with severe constipation People with headaches in the past People taking SSRI drugs in the past
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Systolic Blood pressure. Timepoint: Every two minutes after intervention until the baby is discharged and after that every 5 minutes until the mother is discharged from recovery. Method of measurement: Sa'adat Monitoring Device.;Diastolic Blood pressure. Timepoint: Every two minutes after intervention until the baby is discharged and after that every 5 minutes until the mother is discharged from recovery. Method of measurement: Sa'adat Monitoring Device.;Mean Arterial Pressure (MAP). Timepoint: Every two minutes after intervention until the baby is discharged and after that every 5 minutes until the mother is discharged from recovery. Method of measurement: Sa'adat Monitoring Device.;Heart Rate. Timepoint: Every two minutes after intervention until the baby is discharged and after that every 5 minutes until the mother is discharged from recovery. Method of measurement: Sa'adat Monitoring Device.;Arterial oxygen saturation. Timepoint: Every two minutes after intervention until the baby is discharged and after that every 5 minutes until the mother is discharged from recovery. Method of measurement: Sa'adat Monitoring Device.;Frequency of postoperative nausea and vomiting. Timepoint: From the start of the intervention until three hours after the end of the intervention. Method of measurement: History and clinical examination.;Frequency of chills after surgery. Timepoint: From the start of the intervention until three hours after the end of the intervention. Method of measurement: History and clinical examination.;Cumulative dose of ephedrine. Timepoint: From the start of the intervention until three hours after the end of the intervention. Method of measurement: Researcher-made checklist.;Cumulative dose of atropine drugs. Timepoint: From the start of the intervention until three hours after the end of the intervention. Method of measurement: Researcher-made checklist. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactDr. Ali Fanoodi
Birjand University of Medical Sciences
Outcome results
None listed