Evaluation of the Efficacy of Crocin on metabolic and Weight Loss of Obese Patients Undergoing Sleeve Gastrectomy Bariatric Surgery

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20241023063475N1

Enrollment

Registered

2024-11-24

Start date

2024-12-21

Completion date

Unknown

Last updated

2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Overweight and obesity. Overweight and obesity

Interventions

Intervention 1: Intervention group: A daily dose of 15 mg of crocin (Krocina) will be administered, which will be obtained from Pouyesh Darou Sina Company. The treatment will be given for a duration o

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age range: 20-60 years Obesity candidates for bariatric surgery Normal renal function Normal liver function

Exclusion criteria

Exclusion criteria: sensitivity to crocin substance drug allergy to crocin history of alcohol consumption history of chronic diseases

Design outcomes

Primary

Measure	Time frame
CRP. Timepoint: base and after 90 days. Method of measurement: laboratory kit.;LDL. Timepoint: base and after 90 days. Method of measurement: laboratory kit.;HDL. Timepoint: base and after 90 days. Method of measurement: laboratory kit.;Total Cholesterol. Timepoint: base and after 90 days. Method of measurement: laboratory kit.;AST. Timepoint: base and after 90 days. Method of measurement: laboratory kit.;ALT. Timepoint: base and after 90 days. Method of measurement: laboratory kit.;ALP. Timepoint: base and after 90 days. Method of measurement: laboratory kit.;BUN. Timepoint: base and after 90 days. Method of measurement: laboratory kit.;Creatinine. Timepoint: base and after 90 days. Method of measurement: laboratory kit.;Body Mass Index (BMI). Timepoint: base and after 90 days. Method of measurement: Height measurement tool (stadiometer) and weight measurement tool (scale).;Fasting Blood Sugar. Timepoint: base and after 90 days. Method of measurement: laboratory kit.;Triglyceride. Timepoint: base and after 90 days. Method of measurement: laboratory kit.;Waist circumference. Timepoint: base and after 90 days. Method of measurement: stadiometer.;Waist to hip ratio. Timepoint: base and after 90 days. Method of measurement: stadiometer.;HbA1c. Timepoint: base and after 90 days. Method of measurement: laboratory kit.	—

Measure

Time frame

CRP. Timepoint: base and after 90 days. Method of measurement: laboratory kit.;LDL. Timepoint: base and after 90 days. Method of measurement: laboratory kit.;HDL. Timepoint: base and after 90 days. Method of measurement: laboratory kit.;Total Cholesterol. Timepoint: base and after 90 days. Method of measurement: laboratory kit.;AST. Timepoint: base and after 90 days. Method of measurement: laboratory kit.;ALT. Timepoint: base and after 90 days. Method of measurement: laboratory kit.;ALP. Timepoint: base and after 90 days. Method of measurement: laboratory kit.;BUN. Timepoint: base and after 90 days. Method of measurement: laboratory kit.;Creatinine. Timepoint: base and after 90 days. Method of measurement: laboratory kit.;Body Mass Index (BMI). Timepoint: base and after 90 days. Method of measurement: Height measurement tool (stadiometer) and weight measurement tool (scale).;Fasting Blood Sugar. Timepoint: base and after 90 days. Method of measurement: laboratory kit.;Triglyceride. Timepoint: base and after 90 days. Method of measurement: laboratory kit.;Waist circumference. Timepoint: base and after 90 days. Method of measurement: stadiometer.;Waist to hip ratio. Timepoint: base and after 90 days. Method of measurement: stadiometer.;HbA1c. Timepoint: base and after 90 days. Method of measurement: laboratory kit.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactLeila Torkaman Zadeh

Sabzevar University of Medical Sciences

leila_torkamanzadeh@yahoo.com+98 51 4401 8101

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026