hemodialysis patient. Unspecified kidney failure
Conditions
Interventions
Intervention 1: Control group: they receive a placebo( flour capsules). Intervention 2: Intervention group: hydro alcoholic extract of purslane plant( 100grams of purslane powder is soaked in 500 ml o
Sponsors
Yasouj University of Medical Sciences Research Assistant
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: absence of active infectious diseases, malignancy and other obvious inflammatory diseases age over 18 receive hemodyalysis at least twice a week for about 3 months not using drugs that affect inflammatory indicators such as corticosteroid and NSAIDs in the last month
Exclusion criteria
Exclusion criteria: albumin less than 3 malnutrition and cachexia patient dissatisfaction active infection and malignancy patients who do not want to cooperate language or cognitive problems preventing the patient from completing the questionnaire
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Level of lipid peroxidation and inflammatory markers in chronic hemodialysis. Timepoint: before prescribing the drug and after taking the drug. Method of measurement: with MDA , thiobituric acid produces a red color that can be measured by its light absorption at 535 nm. the amount of inflammatory markers : IL6 and TNFa. TNFa was measured with the Zellbio ELISA kit according to the instructions of the kit and by the sandwich ELISA method. | — |
Secondary
| Measure | Time frame |
|---|---|
| IL6. Timepoint: before and one month after drug administration. Method of measurement: with kata eliza , Zellbio company.;TNFa. Timepoint: before and one month after drug administration. Method of measurement: with kata eliza , Zellbio company. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactMoslem Sedaghat Talab
Yasouj University of Medical Sciences
Outcome results
None listed