Comparison of the effect of dexmedetomidine and pethidine on reducing postoperative shivering in elective lower limb surgery

Comparison the effect of dexmedetomidine and pethidine on reducing postoperative shivering in 18-60 years old patients with elective lower limb surgery

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20241022063464N2

Enrollment

170

Registered

2025-07-06

Start date

2025-05-20

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative shivering.

Interventions

Intervention 1: Intervention group 1: An intravenous infusion of dexmedetomidine (Exir company) at a dose of 1 microgram per kilogram of body weight was diluted in 100 mL of normal saline and administ

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age between 18 and 60 years old Duration of surgery less than 3 hours No cardiovascular past medical history No history of angiography in last 3 month No drug or opioid addiction Elective lower limb surgery

Exclusion criteria

Exclusion criteria: ASA class 3 or 4 Pack cell transfusion Hemodynamic instability during surgery

Design outcomes

Primary

Measure	Time frame
Postoperative shivering. Timepoint: Every 10 minutes from the time of admission to the recovery room up to 30 minutes. Method of measurement: postoperative shivering scale.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactMahrokh Madah

Gorgan University of Medical Sciences

mitramaddah2000@yahoo.com+1731153355

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026