The effect of Intrathecal injection of Pethidine with Bupivacaine on pain control in Appendectomy Surgery

Investigating the effect of Intrathecal injection of Pethidine with Bupivacaine on pain control in Appendectomy Surgery under regional Anesthesia

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20241022063464N1

Enrollment

Registered

2024-12-24

Start date

2024-12-20

Completion date

Unknown

Last updated

2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Appendicitis. Acute appendicitis with generalized peritonitis

Interventions

Intervention 1: Intervention group: group that we inject 12.5mg bupivacaine plus 25mg pethidine in L2-L3 space. Intervention 2: Control group: We inject 12.5 mg bupivacaine plus 0.5 cc strile normal s

Eligibility

Sex/Gender

All

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: Age between 18-60 years old Had a informed consent Acute appendicitis ASA 1 OR 2

Exclusion criteria

Exclusion criteria: Allergy to bupivacaine Allergy to meperidine BMI>30 Difficulty with regional anesthesia(no premission-scoliosis-site infection-neuropathy) Opium addiction

Design outcomes

Primary

Measure	Time frame
Pain. Timepoint: Every 5 minute. Method of measurement: VAS(visual analogue scale).	—

Secondary

Measure	Time frame
Blood pressure. Timepoint: Every 5 min. Method of measurement: Non invase blood pressure.	—

Countries

Iran (Islamic Republic of)

Contacts

Public ContactBabak mojaver aghili

Gorgan University of Medical Sciences

s.sh19441@gmail.com+98 17 3222 0561

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026