Temporomandibular joint osteoarthritis. Temporomandibular joint disorders
Conditions
Interventions
Intervention 1: Intervention group: Taking Anaheal (Bromelain) 500 mg three times a day for 7 days. Intervention 2: Control group: Patients treated with diclofenac sodium tablets 50 mg for 7 days.
Sponsors
Mashhad University of Medical Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients whose osteoarthritis diagnosis has been confirmed by a specialist, based on the patient's history, clinical features, radiographic findings, the onset of symptoms, and bone changes. Patient History: The patient typically complains of unilateral joint pain that worsens with jaw movement. The pain is usually persistent and may intensify in the afternoon or at night. The presence of secondary symptoms, such as central nervous system sensitization, may be observed, manifesting as chronic pain and increased sensitivity to pain. Clinical features: Limitation in jaw opening due to joint pain, a sense of "crepitation" (crackling sound) in the joint, particularly in cases where the condition has been present for a prolonged period, increased pain with pressure on the joint area, and manual loading on the joint. Radiography: The diagnosis is typically confirmed through CBCT imaging of the temporomandibular joint, which reveals structural changes in the subchondral bone (such as flattening, osteophytes, and erosions). Symptom onset: The patient may have symptoms for an extended period (up to 6 months) before sufficient structural changes in the bone are evident on radiographic imaging.
Exclusion criteria
Exclusion criteria:
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain score. Timepoint: Before the intervention and on days 5, 7 and 14 after the intervention. Method of measurement: Visual analog scale.;Mouth opening rate. Timepoint: Before the intervention and on days 5, 7 and 14 after the intervention. Method of measurement: Mouth opening is reported in millimeters between the upper and lower incisors. | — |
Secondary
| Measure | Time frame |
|---|---|
| Jaw deviation. Timepoint: Before the intervention and on days 5, 7 and 14 after the intervention. Method of measurement: Present or absent, jaw deviation is diagnosed by clinical examination when the mouth is closing.;Temporomandibular joint sounds. Timepoint: Before the intervention and on days 5, 7 and 14 after the intervention. Method of measurement: ypes of Temporomandibular joint sounds include clicking, popping, and crepitation. Joint sounds are assessed by the presence or absence of these sounds. These sounds are measured by clinical examination during opening and closing or when the joint is pressed. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public Contactnavid kazemian baghan
Mashhad University of Medical Sciences
Outcome results
None listed