Investigating the effects of acute stress on memory retrieval and frontal alpha waves.
Conditions
Interventions
Intervention 1: Control group: 20 people. On the first day of each experimental session, all participants will receive the necessary training and explanations. On this day, the participants will learn
Sponsors
Semnan University of Medical Sciences
student
Eligibility
Sex/Gender
Male
Age
18 Years to 29 Years
Inclusion criteria
Inclusion criteria: 1-Body mass index (BMI) 18. 5-25 kg/m2 2-No smoking (according to the person's statement) 3-Age: 18-29 4-Not using drugs and alcohol (according to the person himself) 5-Absence of current or past history of mental illness (according to the individual's statement) 6-Not taking medication for physical illness/not taking memory-enhancing drugs (according to the individual's statement) 7-Absence of signs and symptoms of the disease or abnormal laboratory tests (according to the person himself) 8- No family history of mental illness (according to the person himself) 9- informed consent 10- We will only include male participants because fluctuations in sex hormones in female participants can affect hemispheric asymmetry.
Exclusion criteria
Exclusion criteria: 1- Medical illness in the previous 3 weeks (as self-reported) 2- Current or lifelong psychopathology (as self-reported) 3- Cardiovascular disorders (as self-reported) 4- Skin diseases (as self-reported) 5- Left-handedness 6- Current treatment with psychoactive drugs, narcotics, Beta blockers or steroids (self-reported)
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Frontal alpha wave asymmetry in two brain hemispheres. Timepoint: during stress induction. Method of measurement: Recording of brain waves with an electroencephalogram device.;Memory retrieval. Timepoint: One day after stress induction (or control group without stress). Method of measurement: number of memorized words.;Salivary cortisol. Timepoint: at four time points (before, after, and during stress). Method of measurement: immunoassay method. | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood pressure. Timepoint: before drug or placebo (t0). 60 minutes after drug or placebo (t+60). 85 minutes after drug or placebo (t+85). 100 minutes after drug or placebo (t+100). 130 minutes after drug or placebo (t+130). Method of measurement: Digital sphygmomanometer.;Heart rate. Timepoint: before drug or placebo (t0). 60 minutes after drug or placebo (t+60). 85 minutes after drug or placebo (t+85). 100 minutes after drug or placebo (t+100). 130 minutes after drug or placebo (t+130). Method of measurement: Digital sphygmomanometer. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactParisa Keyhanmehr
Semnan University of Medical Sciences
Outcome results
None listed