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Investigating the combined treatment effect of cilostazol and aspirin in acute ischemic stroke

Investigating the effect of dual treatment with cilostazol and aspirin for secondary prevention of acute ischemic stroke

Status
Recruiting
Phases
Phase 3
Study type
Interventional
Source
IRCT
Registry ID
IRCT20241016063386N1
Enrollment
100
Registered
2024-10-30
Start date
2024-11-21
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Ischemic stroke. Cerebellar stroke syndrome

Interventions

Intervention 1: Intervention group: Patients in the intervention group will receive a combined treatment of aspirin 80 mg and cilostazol 200 mg orally daily for 3 months. Intervention 2: Control group

Sponsors

Oroumia University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Age 18 years and older Non-cardioembolic stroke Having a score of less than 20 on the National Institutes of Health Stroke Scale (NIHSS) and a score of 0-2 on the Modified Rating Scale (MRS)

Exclusion criteria

Exclusion criteria: Antiplatelet use including cilostazol, clopidogrel, ticlopidine, aspirin more than 200 mg or any type of anticoagulant before the onset of stroke Bleeding or tendency to bleed Congestive heart failure Malignancy Allergy to cilostazol or salicylic acid or aspirin-induced asthma History of cerebral hemorrhage Platelets less than 10,000 Pregnancy or breastfeeding History of recent gastric ulcer

Design outcomes

Primary

MeasureTime frame
NIHSS score (National Institutes of Health Stroke Scale) as a measure of the amount of disturbance caused in stroke. Timepoint: Before and 3 months after the intervention. Method of measurement: Questionnaire.;MRS score (Modified Rankin Scale). Timepoint: Before and 3 months after the intervention. Method of measurement: Questionnaire.

Secondary

MeasureTime frame
Cerebral hemorrhage. Timepoint: 3 months after the intervention. Method of measurement: MRI.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactDr. Fatemeh Hamzeh

Oroumia University of Medical Sciences

hamzeh.f@umsu.ac.ir+98 44 3345 7286

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026