Efficacy of probiotic mouthwash on early wound healing after crown lengthening

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20241014063362N1

Enrollment

Registered

2025-02-04

Start date

2025-02-19

Completion date

Unknown

Last updated

2025-07-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Early wound healing after surgery.

Interventions

Intervention 1: Intervention group: Probiotic handwash, which includes Lactubacillus rhamnosus, Lactobacillus reuteri and Bifidobacterium infantis bacteria, will be developed in Shahid Sadoughi Facult

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: The patient's age should be more than 18 years. Requires crown lengthening surgery There should be no restrictions on surgery. There is no pathological lesion in the surgical area or in the adjacent teeth The person does not have a history of periodontal disease in the surgical site. He or she has not taken antibiotics for a long time in the past 3 months. He or she has not taken medicine that increases the volume of gums Does not have a diagnosed mental illness Does not smoke or hookah The patient should not take sedatives. The patient is not pregnant. Does not have systemic diseases such as diabetes and cardiovascular diseases The duration of the surgery is a maximum of 90 minutes

Exclusion criteria

Exclusion criteria: The patient does not want to continue participating in the study Unfavorable systemic conditions for the patient during the study.

Design outcomes

Primary

Measure	Time frame
The amount of pain and burning. Timepoint: The next day (by phone call), 3 days later, 1 week later and 1 month later (in face-to-face meeting). Method of measurement: Visual analog scale ( VAS ).;The amount of inflammation and redness. Timepoint: 1 week later and 1 month later (in face-to-face meeting). Method of measurement: Wound Healing Index ( WHI ).;The amount of edema and swelling. Timepoint: 3 days later, 1 week later and 1 month later (in face-to-face meeting). Method of measurement: Wound Healing Index ( WHI ).;Pus secretion. Timepoint: 1 week later and 1 month later (in face-to-face meeting). Method of measurement: Wound Healing Index ( WHI ).;The amount of flap opening. Timepoint: 1 week later and 1 month later (in face-to-face meeting). Method of measurement: Wound Healing Index ( WHI ).	—

Measure

Time frame

The amount of pain and burning. Timepoint: The next day (by phone call), 3 days later, 1 week later and 1 month later (in face-to-face meeting). Method of measurement: Visual analog scale ( VAS ).;The amount of inflammation and redness. Timepoint: 1 week later and 1 month later (in face-to-face meeting). Method of measurement: Wound Healing Index ( WHI ).;The amount of edema and swelling. Timepoint: 3 days later, 1 week later and 1 month later (in face-to-face meeting). Method of measurement: Wound Healing Index ( WHI ).;Pus secretion. Timepoint: 1 week later and 1 month later (in face-to-face meeting). Method of measurement: Wound Healing Index ( WHI ).;The amount of flap opening. Timepoint: 1 week later and 1 month later (in face-to-face meeting). Method of measurement: Wound Healing Index ( WHI ).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactNima Shamsi

Yazd University of Medical Sciences

shamsi.nima78@gmail.com+98 917 032 5228

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026