comparison of Effect of TTNS vs anticholinergic in OAB

Comparison of quality of life and clinical results of posterior tibial nerve stimulation and selective anticholinergic treatment in multiple sclerosis patients with neurogenic bladder in a randomized clinical trial.

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

IRCT

Registry ID

IRCT20241010063320N1

Enrollment

Registered

2024-11-25

Start date

2024-05-02

Completion date

Unknown

Last updated

2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Over active bladder. Other specified disorders of bladder

Interventions

Intervention 1: Intervention group: Treatment with transcutaneous posterior tibial nerve stimulation. Intervention 2: Intervention group: Treatment with selective anticholinergics.

Eligibility

Sex/Gender

All

Age

18 Years to No maximum

Inclusion criteria

Inclusion criteria: Multiple sclerosis confirmed by a neurologist Urodynamic findings based on overactive bladder

Exclusion criteria

Exclusion criteria: Sacral peripheral nerve lesions UTI Specific prostate size in digital rectal examination Bladder outlet obstruction Pregnancy Diabet melitus type 2 Severe cardio_pulmonary disease History of urinary control surgery Current bladder malignancy

Design outcomes

Primary

Measure	Time frame
Questionnaire ICIQ_OAB. Timepoint: Comparison between questionnaires in both groups, one at the beginning of treatment and the other 12 weeks after treatment. Method of measurement: Questionnaire ICIQ_OAB & Questionnaire ICIQ_QOL.;Questionnaire ICIQ_QOL. Timepoint: Comparison between questionnaires in both groups, one at the beginning of treatment and the other 12 weeks after treatment. Method of measurement: Questionnaire ICIQ_QOL.	—

Measure

Time frame

Questionnaire ICIQ_OAB. Timepoint: Comparison between questionnaires in both groups, one at the beginning of treatment and the other 12 weeks after treatment. Method of measurement: Questionnaire ICIQ_OAB & Questionnaire ICIQ_QOL.;Questionnaire ICIQ_QOL. Timepoint: Comparison between questionnaires in both groups, one at the beginning of treatment and the other 12 weeks after treatment. Method of measurement: Questionnaire ICIQ_QOL.

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactZeiab ashoori ghazi mahaleh

Iran University of Medical Sciences

Zeinabashoori1372@gmail.com+98 21 8879 1483

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026