Investigating the side effects of propofol and dexmedetomidine in sedation in cataract surgery

A comparative study of complications during and after cataract surgery in patients under sedation with dexmedetomidine compared with propofol

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

IRCT

Registry ID

IRCT20241009063308N1

Enrollment

184

Registered

2024-12-27

Start date

2024-12-10

Completion date

Unknown

Last updated

2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cataract. Unspecified cataract

Interventions

Intervention 1: Intervention group: Dexmedetomidine with a dose of 6 to 1 microgram per kilogram of body weight at the beginning and then 4 micrograms per kilogram of body weight per hour as a mainten

Eligibility

Sex/Gender

All

Age

60 Years to 80 Years

Inclusion criteria

Inclusion criteria: The patient must be between 60 and 80 years old Patients do not have severe cardiovascular problems The patient is in ASA I and ASA II

Exclusion criteria

Exclusion criteria: The patient has a known allergy to the drug.

Design outcomes

Primary

Measure	Time frame
Delirium. Timepoint: Delirium is investigated in recovery. Method of measurement: The method of measuring the variable is in the form of a questionnaire (has, does not have).	—

Secondary

Measure	Time frame
Blood pressure. Timepoint: Before surgery, during surgery and during recovery. Method of measurement: With monitor.;Respiratory Rate. Timepoint: Before surgery, during surgery and during recovery. Method of measurement: Visually by an anesthesiologist.;Heart Rate. Timepoint: Before surgery, during surgery and during recovery. Method of measurement: With monitor.;Patient satisfaction. Timepoint: After surgery in the ward. Method of measurement: In the form of a questionnaire (low, medium, high satisfaction).;Surgeon's consent. Timepoint: In the operating room after the surgery. Method of measurement: In the form of a questionnaire (low, medium, high satisfaction).;Nausea. Timepoint: In recovery. Method of measurement: In the form of a questionnaire (not satisfied, low, medium, high).;Pain. Timepoint: After surgery in recovery. Method of measurement: Pain ruler.;Apnea. Timepoint: During surgery. Method of measurement: The method of measuring the variable is in the form of a questionnaire (has, does not have).	—

Measure

Time frame

Blood pressure. Timepoint: Before surgery, during surgery and during recovery. Method of measurement: With monitor.;Respiratory Rate. Timepoint: Before surgery, during surgery and during recovery. Method of measurement: Visually by an anesthesiologist.;Heart Rate. Timepoint: Before surgery, during surgery and during recovery. Method of measurement: With monitor.;Patient satisfaction. Timepoint: After surgery in the ward. Method of measurement: In the form of a questionnaire (low, medium, high satisfaction).;Surgeon's consent. Timepoint: In the operating room after the surgery. Method of measurement: In the form of a questionnaire (low, medium, high satisfaction).;Nausea. Timepoint: In recovery. Method of measurement: In the form of a questionnaire (not satisfied, low, medium, high).;Pain. Timepoint: After surgery in recovery. Method of measurement: Pain ruler.;Apnea. Timepoint: During surgery. Method of measurement: The method of measuring the variable is in the form of a questionnaire (has, does not have).

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Countries

Iran (Islamic Republic of)

Contacts

Public ContactNadiya Khademi

Yasouj University of Medical Sciences

Nadiya7899khademi@gmail.com+98 991 531 7431

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026