Chronic renal failure. Chronic kidney disease (CKD)
Conditions
Interventions
Intervention 1: Intervention group: 5 mg melatonin drug by Galenos company, 1 pill daily for 2 months. Intervention 2: Control group: In addition to continuing to take their previous medications, pati
Sponsors
Yasouj University of Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: Patients with chronic kidney disease Patients with persistant proteinuria Able to cooperate and communicate The patient is not on dialysis have signed the consent form to enter the study
Exclusion criteria
Exclusion criteria: Having a severe physical and neurological or psychiatric illness and not being able to continue to cooperate Drug sensitivity or allergic reaction to the drug Patients taking immunosuppressive drugs Patients with liver enzyme disorders Patients with seizure disorders and taking anticonvulsant drugs Patients with depression disorders and taking drugs such as tricyclic antidepressants, fluvoxamine
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Glomerular filtration score of patients with chronic renal failure. Timepoint: At the beginning of the study (before the start of the intervention) and 1 month later and 2 months after the start of the intervention. Method of measurement: Measurement of patient's serum creatinine level.;The amount of proteinuria in chronic renal failure patients. Timepoint: At the beginning of the study (before the start of the intervention) and 1 month later and 2 months after the start of the intervention. Method of measurement: Measuring protein excretion in 24-hour urine.;Appetite score of patients with chronic renal failure. Timepoint: At the beginning of the study (before the start of the intervention) and 1 month later and 2 months after the start of the intervention. Method of measurement: Intensive nutritional assessment questionnaire. | — |
Secondary
| Measure | Time frame |
|---|---|
| The amount of changes in the glomerular filtration score of patients with chronic renal failure. Timepoint: The beginning of the study (before the start of the intervention) and 1 month and 2 months after the start of the intervention. Method of measurement: Measurement of patient's serum creatinine level.;The amount of proteinuria changes in patients with chronic renal failure. Timepoint: The beginning of the study (before the start of the intervention) and 1 month and 2 months after the start of the intervention. Method of measurement: The rate of protein excretion in 24-hour urine.;The amount of changes in the appetite score of patients with chronic renal failure. Timepoint: The beginning of the study (before the start of the intervention) and 1 month and 2 months after the start of the intervention. Method of measurement: Intensive nutritional assessment questionnaire. | — |
Countries
Iran (Islamic Republic of)
Contacts
Public ContactAbbasi, Hamidreza
Yasouj University of Medical Sciences
Outcome results
None listed