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Comparison of preventive effect of tramadol and acetaminophen on control of postoperative pain after elective abdominal surgery under general anesthesia

Comparison of preventive effect of tramadol and acetaminophen on control of postoperative pain after elective abdominal surgery under general anesthesia

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
IRCT
Registry ID
IRCT20241006063269N1
Enrollment
90
Registered
2024-10-11
Start date
2024-11-05
Completion date
Unknown
Last updated
2025-01-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Elective abdominal surgery patients. Surgical follow-up care, unspecified

Interventions

Intervention 1: First intervention group: 500 mg oral acetaminophen. Treatment method, we have used multimodal treatment in this study. Prescribing pain medication before surgery is one of the natural

Sponsors

Oroumia University of Medical Sciences
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: Patients over 18 years old Volunteer

Exclusion criteria

Exclusion criteria: history of seizures History of upper gastrointestinal bleeding related to previous NSAID treatment kidney deficiency ( cr >1.6) History of alcohol, opioid Use of NSAIDs or acetaminophen within the last 24 hours Allergy to study drugs (tramadol or acetaminophen)

Design outcomes

Primary

MeasureTime frame
Reduce the postoperative pain _ Numeric rating scale (NRS). Timepoint: Pain intensity will be assessed as mild (NRS: 0-3), moderate (NRS: 4-6) and severe (NRS: 7-10). The NRS score during recovery is recorded at 2, 4, 6, 8, 12, and 24 hours after the patient fully wakes up from anesthesia. Method of measurement: Patient date and Numerical Pain Rating Scale (NRS) questionnaire.

Secondary

MeasureTime frame
Nausea and vomiting and other complication. Timepoint: From the end of the operation until the patient feels nausea and vomiting and other complication. Method of measurement: Patient reports and observations and records of patient data.

Countries

Iran (Islamic Republic of)

Contacts

Public ContactAli Akbar Nasiri

Oroumia University of Medical Sciences

nasiriali7@gmail.com+98 44 3322 4009

Outcome results

None listed

Source: IRCT (via WHO ICTRP) · Data processed: Feb 4, 2026